Results 131 to 140 of about 752,866 (297)

An in vitro neurobacterial interface reveals direct modulation of neuronal function by gut bacteria

Scientific Reports
Interactions between bacteria and somatic cells are increasingly important for understanding cellular communication mechanisms. While the gut microbiome’s influence on the gut–brain axis is established, direct interactions between bacteria and neurons ...
Juan Lombardo-Hernandez, Jesús Mansilla-Guardiola, Riccardo Aucello, Cristian Botta, Maria Teresa García-Esteban, Antonio Murciano-Cespedosa, David Muñoz-Rodríguez, Elisa Quarta, Álvaro Mateos González, Carmen Juan-Llamas, Kalliopi Rantsiou, Stefano Geuna, Luca Cocolin, Celia Herrera-Rincon   +13 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Genetic diversity and population structure of locally adapted South African chicken lines: Implications for conservation.

, 2008
In this study microsatellite markers were applied to investigate the genetic diversity and population structure of the six local chicken lines kept in the “Fowls for Africa” program, for better clarification of parameters for breed differentiation and ...
Hefer, C.A., Groenen, M.A.M., Nel, L.H., Marle-Koster, E., van   +3 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Proteomics for Bioenergy Production

, 2017
This chapter reviews the importance and application of proteomics tools for studying bioenergy crops and microorganisms employed in sugar fermentation and/or degradation of cell wall compounds.
Salvato, Fernanda, DoNascimento, D. D., Pickering, W. A., Gutierrez Rodriguez, Edwin Antonio [UNESP], Santana Costa, Marilia Gabriela de [UNESP], Santos, Bruna Marques dos [UNESP]   +5 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Sparse experimental design : an effective an efficient way discovering better genetic algorithm structures

, 2001
The focus of this paper is the demonstration that sparse experimental design is a useful strategy for developing Genetic Algorithms. It is increasingly apparent from a number of reports and papers within a variety of different problem domains that the ...
Pongcharoen, P., Whitfield, R.I., Braiden, P. M., Stewardson, D.J., Braiden, P., Hicks, C.   +5 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Climatic niche and neutral genetic diversity of the six Iberian pine species: a retrospective and prospective view

, 2010
Quaternary climatic fluctuations have left contrasting historical footprints on the neutral genetic diversity patterns of existing populations of different tree species.
Soto de Viana, Álvaro
core   +1 more source

Editorial: Ecosystem Approach to Fisheries in the Mediterranean and Black Seas - Advances in Research and Technologies

Frontiers in Marine Science, 2020
Violin Stoyanov Raykov, Petya Pavlova Ivanova, Cemal Turan, Ertug Duzgunes   +3 more
doaj   +1 more source