Results 91 to 100 of about 752,866 (297)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
On the Breeds of Cattle—Historic and Current Classifications [PDF]
, 2011 Classification of cattle breeds contributes to our understanding of the history of cattle and is essential for an effective conservation of genetic diversity.
Koolmees, Peter A. +18 more
core +1 more source
FlyDrosophila melanogaster is a highly versatile model organism that has profoundly advanced our understanding of human diseases. With more than 60% of its genes having human homologs, Drosophila provides an invaluable system for modelling a wide range of ...
Ayomide Victor Atoki +8 more
doaj +1 more source
Genetic monitoring tools for radon pollution research [PDF]
BIO Web of ConferencesA critical target for ionizing radiation is DNA that damage to a cell. Thus, when dealing with the general irradiation of the body, we observe the diverse effects of radiation.
Biyasheva Zarema +3 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
The molecular epidemiology of parasite infections: Tools and applications
, 2012 Molecular epidemiology, broadly defined, is the application of molecular genetic techniques to the dynamics of disease in a population. In this review, we briefly describe molecular and analytical tools available for molecular epidemiological studies and
Thompson, R.C.A., Lymbery, A.J.
core
Genetic modification of Streptococcus dysgalactiae by natural transformation
mSphereStreptococcus dysgalactiae is an emerging human and animal pathogen. Functional studies of genes involved in virulence of S. dysgalactiae and other pyogenic group streptococci are often hampered by limited genetic tractability.
Marita Torrissen Mårli +4 more
doaj +1 more source
Computational Tools to Investigate Genetic Cardiac Channelopathies
Frontiers in Physiology, 2013 NA
Hugues eAbriel +4 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source