Results 61 to 70 of about 752,866 (297)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Predicting regression test failures using genetic algorithm-selected dynamic performance analysis metrics

, 2013
A novel framework for predicting regression test failures is proposed. The basic principle embodied in the framework is to use performance analysis tools to capture the runtime behaviour of a program as it executes each test in a regression suite.
Simon Spacey, Michael Mayo, Mayo, Michael, Spacey, Simon   +3 more
core   +1 more source

Engineered genetic tools for directed gene regulation [PDF]

, 2019
Genetic manipulation or genetic engineering is the ability to modify the behaviour of a gene or group of genes. In biological research, since nucleic acids were shown to be responsible for control of cellular functions and transfer of biological ...
Rinaldi Ferreira, Rafael
core   +1 more source

A Cutter Selection Method for 2 1/2-Axis Trochoidal Milling of the Pocket Based on Optimal Skeleton

IEEE Access, 2022
The trochoidal toolpath is generated based on skeleton. However, several different skeletons can be extracted from one pocket. To improve the efficiency of trochoidal rough milling, a cutter selection method basing the optimal skeleton is proposed ...
Feiyan Han, Longlong He, Zhitao Hu, Chuanwei Zhang   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay. [PDF]

, 2011
The diversity in the Plasmodium falciparum genome can be used to explore parasite population dynamics, with practical applications to malaria control.
Abdoulaye Djimde, Newbold, CI, Steven M Kiara, MacInnis, B, Jiang Hongying, Amaratunga, Chanaki, Mangano Valentina, Panos Deloukas, Socheat, Duong, Kirk Rockett, Jiang, H, Kivinen, K, MacInnis Bronwyn, Borrmann Steffen, Kwiatkowski, DP, Kiara Steven M., Kwiatkowski, Dominic, Pascal Michon, Valentina Mangano, Dominic P Kwiatkowski, Kwiatkowski Dominic P., Taane G Clark, Djimde Abdoulaye, Christopher I. Newbold, Borrmann, S, Deloukas, P, Rockett, K, Su, X-Z, Dominic P. Kwiatkowski, Nicholas J White, Imwong, Mallika, Ouedraogo, JB, Anderson, Timothy, Nicholas J. White, White Nicholas J., Zongo Issaka, Campino, S, Taane G. Clark, MacInnis, Bronwyn, Auburn Sarah, Clark, Taane G, Clark, TG, Newbold, Christopher, Nosten, François, Issaka Zongo, Nzila, A, Rockett Kirk, Gwilliam Rhian, Kevin Marsh, Djimde, Abdoulaye, Newbold, Christopher I, Xin-Zhuan Su, Kivinen, Katja, Amaratunga Chanaki, Rhian Gwilliam, Nosten François, Susana Campino, White, Nicholas J, Sarah Auburn, Fairhurst, Rick M, Michon, P, Nzila, Alexis, Gwilliam, Rhian, Mueller, Ivo, Siba, P, Doumbo Ogobara K., Ivo Mueller, Marsh, K, Zongo, Issaka, Chanaki Amaratunga, Timothy Anderson, Christopher I Newbold, Imwong Mallika, Jean-Bosco Ouedraogo, Clark Taane G., Alexis Nzila, Socheat Duong, Imwong, M, Anderson, T, Kiara, SM, White, NJ, Marsh, Kevin, Jean Bosco Ouedraogo, Fairhurst, RM, Steven M. Kiara, Michon, Pascal, Doumbo, Ogobara K, Deloukas, Panos, Marsh Kevin, Su, Xin-Zhuan, Djimde, A, Peter Siba, Siba, Peter, Mueller, I, Mallika Imwong, Ogobara K. Doumbo, Anderson Timothy, Hongying Jiang, White, Nicholas, Gwilliam, R, Katja Kivinen, Kiara, Steven M, Michon Pascal, Mangano, V, Siba Peter, Kivinen Katja, Zongo, I, Mueller Ivo, Campino Susana, Rick M. Fairhurst, Amaratunga, C, Newbold Christopher I., Auburn, Sarah, Xin Zhuan Su, Auburn, S, Rockett, Kirk, Bronwyn Macinnis, Nzila Alexis, Duong Socheat, François Nosten, Nosten, F, Su, XZ, Ouedraogo Jean-Bosco, Ouedraogo, J-B, Ogobara K Doumbo, Campino, Susana, Socheat, D, Jiang, Hongying, Doumbo, OK, Su Xin-Zhuan, Mangano, Valentina, Rick M Fairhurst, Ouedraogo, Jean-Bosco, Fairhurst Rick M., Borrmann, Steffen, Steffen Borrmann, Deloukas Panos, Kwiatkowski, Dominic P   +137 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Gene-associated markers provide tools for tackling illegal fishing and false eco-certification

, 2012
Illegal, Unreported and Unregulated fishing has had a major role in the overexploitation of global fish populations. In response, international regulations have been imposed and many fisheries have been 'eco-certified' by consumer organizations, but ...
Hansen, Jakob Hemmer, Puyet, Antonio, Ogden, R., Volckaert, Filip A M, Smith J. P., Taylor M, Waples RS, Geffen A. J., Aoidh EM, Limborg MT, Maes, Gregory E, Waples, R.S., Bautista, Jose M., Smith, Jane P, Jeráme, Marc, McEwing, Ross, Nielsen, Einar E, Panitz F., Bekkevold D., MCEWING Ross, Vieites Baptista, Juan M, Limborg, Morten, Bekkevold D, Gonzalez E, PANITZ Frank, Trentini M., Guarniero, Ilaria, Espiñeira, Montserrat, Albin, Jan E J, Bekkevold, Dorte, Helyar, Sarah, Rastorguev S, Tinti, F., Bendixen C, Limborg, Morten T., FishPop Trace Consortium, Taylor M., Albin, Jan Ej, Piccinetti C, Hemmer Hansen J, Nielsen EE, McEwing R, Gonzalez, Elena, Espiñeira M, González-Lavín N., Piccinetti, Corrado, TAYLOR Martin, HemmerHansen, Jakob, McEwing, R., Diopere, E., Milano, I., Volkov A., Bargelloni, Luca, Bautista, José M, Jerome, Marc, Puyet A, Patarnello, Tomaso, Carvalho G. R., Diez, Amalia, Geffen, Audrey J, Carvalho, Gary R., Carvalho, G.R., Piccinetti C., LIMBORG Morten, González Lavín N, Albin JE, Martinsohn, J. Th., Gonzalez E., Guarniero I, Ogden R., Trentini, Massimo, Milano, Ilaria, Kochzius, Marc, Zanzi, Antonella, Ogden R, BABBUCCI Massimilliano, Waples, Robin S, Mac Aoidh, Eoin, McEwing R., Bergé, Jean-Pascal, Limborg, M.T., Ogden, Rob, Diopere, Eveline, Negrisolo, Enrico, Grenfell, L., Patarnello, T., Martinsohn JT, J. M. Barmintsev, Maes, G.E., CARIANI Alessia, Zanzi A, Diopere E., Limborg M. T., MARTINSOHN Jann, Carvalho GR, Volkov, Alexander, Aoidh, Eoin Mac, DIOPERE Eveline, Bautista JM, Espiñeira M., MAES Gregory, FishPopTrace Consortium, Hemmer-Hansen, J., Taylor, Martin, BARGELLONI Luca, J. K. J. Volckaert, Maes GE, Verrez-Bagnis, Véronique, Babbucci, Massimiliano, Hemmer-Hansen J., Barmintsev, Vladimir, Bargelloni, L., Trentini M, Tinti, Fausto, Taylor, M., Van Houdt, Mouchel O, J. E. J., Barmintsev V, BEKKEVOLD Dorte, CARVALHO Gary R., Mouchel, Olivier, R. S. Albin, Grenfell, Leonie, Van Houdt, J.K.J., Martinsohn, J.T., C. Bergé, J. M. Bendixen, Van Houdt, Jeroen K J, González-Lavín, Nerea, Van Houdt, Jeroen K.J., MAC AOIDH Eoin, J. -P., Helyar, S., Babbucci M., NIELSEN Einar Eg, Van Houdt JK, Panitz, Frank, Krey, Grigorius, FishPopTrace consortium,, PARTANELLO Tomaso, Van Houdt, Jeroen, Bargelloni L., Carvalho, Gary R, Maes, Gregory, VLOCKAERT Filip, Grenfell L., Aoidh, Eion Mac, Kochzius M., Maes, Gregory E., Aoidh E. M., Nielsen, Einar E., Krey G., Mac Aoidh, E., Negrisolo E., Volckaert, Filip A.M., F. A. M. Waples, Bendixen, Christian, Nielsen, E.E., VAN HOUDT Jeroen Kj, Helyar S., Volkaert, Filip, Blohm D, Cardazzo B., Bergé JP, Guaniero, Ilaria, Smith JP, Waples, Robin, Martinsohn J. T., MILANO Ilaria, WAPLES Robin S, Verrez Bagnis V, Puyet A., Nielsen, Einar, Volckaert FA, HEMMER-HANSEN Jakob, Jeráme M, Hemmer-Hansen, Jakob, Cariani A, Krey G, Volckaert, Filip A. M., Volckaert, F.A.M., Limborg, Morten T, Blohm, Dietmar, Cariani, Alessia, Milano I, Maes G. E., Guarniero I., Tinti F, Mouchel O., Vieites Baptista JM, Grenfell L, Waples, Robin S., HEYLAR Sarah, Bekkevold, D., Diez A, Volkov A, Helyar S, NEGRISOLO, ENRICO MASSIMILIANO, Tinti F., V. Bautista, Blohm D., Nielsen E. E., OGDEN Rob, Diopere E, Diez A., Babbucci, M., van Houdt, Jeroen K. J., Verrez-Bagnis V., Geffen, Audrey J., GRENFELL Leonie, Vieites Baptista, Martinsohn, Jann T., Eg Nielsen, Einar, Martinsohn, Jann T, Carvalho, Gary, Jeráme M., Cariani, A., Kochzius M, Cariani A., Martinsohn, Jann, Geffen AJ, Panitz, F., Rastorguev S., Aoidh, E.M., Rastorguev, Sergey, TINTI Fausto, Panitz F, Zanzi A., Cardazzo, Barbara   +229 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Novel genetic tools for Hansenula polymorpha [PDF]

FEMS Yeast Research, 2011
Hansenula polymorpha is an important yeast in industrial biotechnology. In addition, it is extensively used in fundamental research devoted to unravel the principles of peroxisome biology and nitrate assimilation. Here we present an overview of key components of the genetic toolbox for H. polymorpha.
Ruchi, Saraya, Arjen M, Krikken, Jan A K W, Kiel, Richard J S, Baerends, Marten, Veenhuis, Ida J, van der Klei   +5 more
openaire   +2 more sources