Results 201 to 210 of about 546,143 (293)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Fusiform nanoparticle boosts efficient genetic transformation in Sclerotinia sclerotiorum. [PDF]

J Nanobiotechnology
Ding Y, Yang N, Lu Y, Xu J, Rana K, Chen Y, Xu Z, Qian W, Wan H.   +8 more
europepmc   +1 more source

GENETIC TRANSFORMATION IN HEMOPHILUS INFLUENZAE. Annual Progress Report, September 15, 1971--September 14, 1972.

, 1972
Roger M. Herriott
openalex   +2 more sources

Transformation as a tool for genetic fine mapping of closely located mutations inThermus thermophilus [PDF]

, 1994
Takayuki Hoshino, Yuki Hidaka, Takehide Kosuge, Masumi Hasegawa, T. Saito, Tadaatsu Nakahara   +5 more
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

A novel approach: enhancing marigold (Tagetes erecta L.) genetic transformation through seed priming technology. [PDF]

Front Plant Sci
Huang WQ, Meng C, Zhang L, Xu F, Yang XM, Zhang LF, Jiang YL, Shi RX, Zhao AX, Zhang YP, Ali N, Chen XH.   +11 more
europepmc   +1 more source

Role of bacteriophage in the acquisition of competence for genetic transformation and transfection in Staphylococcus aureus and related studies

, 1979
Nancy E. Thompson
openalex   +1 more source

Bacterial gene transfer by natural genetic transformation in the environment. [PDF]

, 1994
Michael G. Lorenz, Wilfried Wackernagel
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Establishment of a genetic transformation system for cordycipitoid fungus Cordyceps chanhua. [PDF]

Front Microbiol
Cai R, Xiao Y, Xing J, Yu K, Li X, Chai Y.   +5 more
europepmc   +1 more source