Results 251 to 260 of about 1,004,687 (332)

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

Molecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

Elucidating the Molecular Mechanisms of Physiological Fruit Abscission in <i>Actinidia arguta</i> Through Comparative Transcriptomics and Transient Genetic Transformation. [PDF]

Plants (Basel)
Yuan P, Wang Y, Sun Y, Liu G, Qin H, Fan S, Yan Y, Sun B, Lu W.   +8 more
europepmc   +1 more source

Genetic transformation of brassica napus via agrobacterium spp. and the development of herbicide resistance.

, 1989
Pierre Charest
openalex   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Establishment of a Genetic Transformation and Gene Editing Method by Floral Dipping in Descurainia sophia. [PDF]

Plants (Basel)
Jia T, Yang H, Zhou D, Zhao S, Wang J, Zhang T, Huang M, Kong D, Liu Y.   +8 more
europepmc   +1 more source

Neisseria lactamica and Neisseria polysaccharea as possible sources of meningococcal beta-lactam resistance by genetic transformation

, 1990
Juan Antonio Sáez-Nieto, Ricardo García Luján, Joaquı́n V. Martı́nez-Suárez, S. Berrón, Julio A. Vázquez, Miguel Viñas, José Campos   +6 more
openalex   +1 more source

Experiment in Genetic Transformation

The American Biology Teacher, 1975
openaire   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Genetic transformation of GmFBX322 gene and salt tolerance physiology in soybean. [PDF]

PLoS One
He H, Zhang Y, Xu S, Zhang X, Yang X, Cheng Y.   +5 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source