Results 281 to 290 of about 1,032,830 (329)

Exploring Agrobacterium-mediated genetic transformation methods and its applications in Lilium. [PDF]

Plant Methods
Fan X, Sun H.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Efficient Plant Regeneration and Transient Genetic Transformation System of <i>Prunus xueluoensis</i> via an <i>Agrobacterium</i>-Mediated Method. [PDF]

Int J Mol Sci
Lin YY, Wu SH, Chen J, Yi XG, Wang XR, Li M.   +5 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Preliminary establishment of genetic transformation system for embryogenic callus of Acer truncatum 'Lihong'. [PDF]

Front Plant Sci
Yang Y, Chan Y, Wang Y, Guo H, Song L, Zhang H, Sun L, Cong R, Zhang H.   +8 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Breeding Maize Hybrids with Improved Drought Tolerance Using Genetic Transformation. [PDF]

Int J Mol Sci
Li Z, Zhang J, Song X.
europepmc   +1 more source

Advancements in delivery strategies and non-tissue culture regeneration systems for plant genetic transformation. [PDF]

Adv Biotechnol (Singap)
Wu M, Chen A, Li X, Li X, Hou X, Liu X.
europepmc   +1 more source

Correction: Exploring Agrobacterium-mediated genetic transformation methods and its applications in Lilium. [PDF]

Plant Methods
Fan X, Sun H.
europepmc   +1 more source

[Dynamic changes in genetic mutations in myelodysplastic neoplasms with progressive disease and leukemic transformation].

Yan Xu, H Y Chen, Luyao Wang, Yali Tian, Yan Gu, Na Liu, Zheng Ge   +6 more
openalex   +2 more sources