Results 171 to 180 of about 566,900 (297)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

EpiMolBio: A novel user-friendly bioinformatic program for genetic variability analysis. [PDF]

Comput Struct Biotechnol J
Reinosa R, Troyano-Hernáez P, Valadés-Alcaraz A, Holguín Á.   +3 more
europepmc   +1 more source

Genetic and genomic variability of Legionella pneumophila: applications to molecular epidemiology and public health.

, 2015
Leonor Sánchez-Busó
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Consanguinity and rare monogenic systemic autoinflammatory disorders: implications for prevalence and genetic variability. [PDF]

Pediatr Rheumatol Online J
AlSaleem A, Al-Mayouf SM.
europepmc   +1 more source

Associations of dietary cholesterol consumption with incident diabetes and cardiovascular disease: the role of genetic variability in cholesterol absorption and disease predisposition

Shuxiao Shi, Ying Dong, Sujing Wang, Xihao Du, Nannan Feng, Lan Xu, Victor W. Zhong   +6 more
openalex   +1 more source

A Massively Parallel Sequencing Approach Uncovers Ancient Origins and High Genetic Variability of Endangered Przewalski's Horses [PDF]

, 2011
Hiroki Goto, Oliver A. Ryder, Allison R. Fisher, Bryant M. Schultz, Sergei L. Kosakovsky Pond, Anton Nekrutenko, Kateryna D. Makova   +6 more
openalex   +1 more source

GENETIC VARIABILITY AND POLYMORPHISM: SYNTHESIS

Cold Spring Harbor Symposia on Quantitative Biology, 1955
openaire   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Genetic Variability in NKG2 Receptors and Their Ligands: Associations with SARS-CoV-2 Infection and COVID-19 Severity. [PDF]

Genes (Basel)
Siemaszko J, Grad K, Świerkot J, Bogunia-Kubik K.   +3 more
europepmc   +1 more source