Genetic variability of host-parasite relationship traits: utilization of isofemale lines in a Drosophila simulans parasitic wasp [PDF]
Y. Carton, Pierre Capy, Anthony J. Nappi
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Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
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EpiMolBio: A novel user-friendly bioinformatic program for genetic variability analysis. [PDF]
Reinosa R+3 more
europepmc +1 more source
Genetic variability in Muscari comosum (Liliaceae). I. A comparative analysis of chromosome polymorphisms in Spanish and Aegean populations [PDF]
Manuel Ruíz-Rejón+1 more
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Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi+12 more
wiley +1 more source
The Influence of Spatial Distance and Environment on Small-Scale Genetic Variability in Eelgrass and Its Application for Restoration. [PDF]
Jahnke M+7 more
europepmc +1 more source
Population crash, population flush and genetic variability in cage populations of Drosophila melanogaster [PDF]
F.A. Lints, Marion Bourgois
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Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham+21 more
wiley +1 more source
Genetic variability of submergence tolerance in rice related to yield and yield contributing traits
MR Islam
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