Results 211 to 220 of about 4,243,841 (306)

Genetic Variability, Trait Association, and Multi-Trait Selection of New Indeterminate Tomato Genotypes Under Protected Cultivation. [PDF]

Plants (Basel)
Shekhar R, Singh AK, Yadav RK, Choudhary H, Asrey R, Mishra GP, Narayanswami B, Chaukhande P, Gainiamliu KG, Mutthuraju C, Kumar R, Pal S, Shaktawat C, Singh N, Singh J.   +14 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Assessment of genome-wide genetic variability and population divergence of four native Turkish sheep breeds. [PDF]

Mamm Genome
Karslı BA, Demir E, Bilginer U, Karslı T, Kaya S, Doğru H, Kara I, Atmaca V, Kaşıkçı D, Koçak S, Yağcı S, Balcıoğlu MS, Lasagna E, Gülyüz F.   +13 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Genetic variability and intra-genotype recombination of DuCV from ducks and geese in central and north China. [PDF]

Front Vet Sci
Wang H, Dong Y, Hu X, Wang J, Xu X, Li D, Ji J, Yao L, Bi Y, Xie Q.   +9 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Genetic Variability and Conserved T-Cell Epitope Prediction of the HPV16 E1 Protein in Cervix Samples from Peru. [PDF]

Pathogens
Bonifacio-Velez de Villa E, Aguilar-Luis MA, Silva-Caso W, Becerra-Goicochea L, Tarazona-Castro Y, Aguilar-Luis D, Denegri-Hinostroza D, Cornejo-Tapia A, Aquino-Ortega R, Del Valle-Mendoza J.   +9 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Genetic variability in thrombopoietin receptor and GATA1 influences response to eltrombopag in dengue-induced thrombocytopenia. [PDF]

Sci Rep
Sayem M, Rimon RA, Alam S, Saba AA, Sanyal M, Sayem M, Tabassum CT, Amin MR, Chakraborty S, Kabir A, Nabi AHMN.   +10 more
europepmc   +1 more source