Results 211 to 220 of about 668,410 (314)

Genetic variability, N-glycosylation, and recombination in sublineage 1A of <i>Betaarterivirus americense</i> from commercial pig farms in Lima, 2019. [PDF]

Front Microbiol
Cotaquispe Nalvarte RY, Legua Barrios M, De la Cruz Vásquez E, Ecos Espino JC, Llona García E, Reyes Ruiz AL, Medina Guerrero MI, Camargo Paredes FK, Coila De la Cruz HV, Mejía Vargas E, Mendoza Yáñez CA, Cabrel Palomares CL, Toskano Hurtado J.   +12 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Whole Genome Sequencing Reveals Genetic Variability of <i>Escherichia coli</i> Across Dairy Farm Environments. [PDF]

Antibiotics (Basel)
Veloo Y, Rajendiran S, Rahman SA, Zakaria Z, Thahir SSA.   +4 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Are Seasonal Acclimation and Genetic Variability of <i>Lobaria pulmonaria</i> Relevant for Conservation Translocation? A Case Study Along a Latitudinal Gradient in Italy. [PDF]

Plants (Basel)
Di Nuzzo L, Agostini M, Benesperi R, Ravera S, Bianchi E, Corneti S, Del Vecchio S, Francesconi L, Gheza G, Paoli L, Nascimbene J.   +10 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A new highly discriminatory typing scheme for <i>Treponema pallidum</i> reveals similar levels of genetic variability across lineages. [PDF]

mBio
Pla-Díaz M, Giacani L, Tantalo LC, Bose M, Reid TB, Marra CM, Šmajs D, Pospíšilová P, Janečková K, Kawahata T, Banno F, Vilfort K, Cao W, Pillay A, Noda A, Bosshard PP, Chen M, Mitjà O, Schuenemann VJ, Hackl S, Nieselt K, Hernández-Bel P, Ocete MD, Arora N, González-Candelas F.   +24 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Mutagenic and physiological impacts of colchicine on growth, flowering behavior, and ISSR-based genetic variability in Calendula officinalis L. [PDF]

BMC Plant Biol
Hassan MA, Saudy HS, Hewidy M, El-Sammak H.   +3 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source