Results 201 to 210 of about 668,410 (314)

Genetic Variability and Conserved T-Cell Epitope Prediction of the HPV16 E1 Protein in Cervix Samples from Peru. [PDF]

Pathogens
Bonifacio-Velez de Villa E, Aguilar-Luis MA, Silva-Caso W, Becerra-Goicochea L, Tarazona-Castro Y, Aguilar-Luis D, Denegri-Hinostroza D, Cornejo-Tapia A, Aquino-Ortega R, Del Valle-Mendoza J.   +9 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Genetic variability of sweet maize kernel phytochemicals

Sweet maize (Zea mays L. saccharata) is widely used in human nutrition due to its sweetness and aroma. The increased demand and production of sweet maize require more attention for profiling the nutritional quality of the kernel.
Mladenović Drinić, Snežana, Srdić, Jelena, Dragičević, Vesna, Brankov, Milan, Simic, Milena, Perić, Vesna, Vukadinović, Jelena   +6 more
core  

Modeling temporal genetic variability using mixed models improves yield stability and selection efficiency in <i>Coffea canephora</i>. [PDF]

Front Plant Sci
Campanharo A, Gonçalves Júnior DH, Daros M, da Cruz LM, Marques I, de Oliveira RR, Partelli FL.   +6 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Factors Influencing Wheat Yield and Variability: Evidence from Manitoba, Canada

Production functions to explain regional wheat yields have not been studied extensively in the Canadian prairies. The objective of this study is to employ a Just-Pope production function to examine the relationship between fertilizer inputs, soil quality,
Grant, Cynthia, Smith, Elwin G., Carew, Richard   +2 more
core  

Genetic variability in thrombopoietin receptor and GATA1 influences response to eltrombopag in dengue-induced thrombocytopenia. [PDF]

Sci Rep
Sayem M, Rimon RA, Alam S, Saba AA, Sanyal M, Sayem M, Tabassum CT, Amin MR, Chakraborty S, Kabir A, Nabi AHMN.   +10 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Genetic variability and response to sertraline in pediatric populations: a review on pharmacogenetics, pharmacokinetics, and the risk of adverse events. [PDF]

Front Child Adolesc Psychiatry
Gándara-Mireles JA, Loera Castañeda V, Lares-Asseff I, Grijalva Ávila JC, Rosales Ramos MM, Villanueva Fierro I, Patrón Romero L, Almanza Reyes H.   +7 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source