Results 21 to 30 of about 99,428 (256)

Feedback Regulation and its Efficiency in Biochemical Networks [PDF]

, 2015
Intracellular biochemical networks fluctuate dynamically due to various internal and external sources of fluctuation. Dissecting the fluctuation into biologically relevant components is important for understanding how a cell controls and harnesses noise ...
Aihara, Kazuyuki, Kobayashi, Tetsuya J., Yokota, Ryo   +2 more
core   +2 more sources

Modeling methylation data as an additional genetic variance component

BMC Proceedings, 2018
High-throughput platforms allow the characterization of thousands of previously known methylation sites. These platforms have great potential for investigating the epigenetic effects that are partially responsible for gene expression control. Methylation
Marcio Almeida, Juan Peralta, Jose Garcia, Vincent Diego, Harald Goring, Sarah Williams-Blangero, John Blangero   +6 more
doaj   +1 more source

Decomposition of multivariate phenotypic means in multigroup genetic covariance structure analysis [PDF]

, 1992
Observed differences in phenotypic means between groups such as parents and their offspring or male and female twins can be decomposed into genetic and environmental components.
A. C. Heath, A. C. Heath, B. Muthén, C. V. Dolan, C. V. Dolan, Conor V. Dolan, D. I. Boomsma, D. I. Boomsma, D. Sörbom, D. Sörbom, D. Sörbom, Dorret I. Boomsma, J. J. McArdle, J. J. McArdle, J. K. Hewitt, J. K. Hewitt, J. P. Royston, K. G. Jöreskog, K. G. Jöreskog, K. Mather, K. V. Mardia, L. J. Eaves, M. Grossman, M. W. Browne, N. G. Martin, Peter C. M. Molenaar, S. G. Vandenberg   +26 more
core   +3 more sources

Equivalence of multibreed animal models and hierarchical Bayes analysis for maternally influenced traits

Genetics Selection Evolution, 2010
Background It has been argued that multibreed animal models should include a heterogeneous covariance structure. However, the estimation of the (co)variance components is not an easy task, because these parameters can not be factored out from the inverse
Cantet Rodolfo JC, Munilla Leguizamón Sebastián   +1 more
doaj   +1 more source

Forecasting the SST space-time variability of the Alboran Sea with genetic algorithms [PDF]

, 1999
We propose a nonlinear ocean forecasting technique based on a combination of genetic algorithms and empirical orthogonal function (EOF) analysis. The method is used to forecast the space-time variability of the sea surface temperature (SST) in the ...
A. Torcini, A. Torcini, Alessandro Torcini, B. I. Shraiman, B. Janiaud, D. A. Egolf, H. Chaté, H. Sakaguchi, Lutz Brusch, M. Bazhenov, M. C. Cross, M. Kness, M. Or-Guil, M. van Hecke, Markus Bär, Martin van Hecke, Martín G. Zimmermann, N. Mukolobwiez, R. Montagne, R. Montagne, T. Bohr, W. van Saarloos, W. van Saarloos   +22 more
core   +6 more sources

Genetic Correlation Between the P300 Event-Related Brain Potential and the EEG Power Spectrum [PDF]

, 2001
Previous studies have demonstrated moderate heritability of the P300 component of event-related brain potentials (ERPs) and high heritability of background electroencephalogram (EEG) power spectrum.
Anokhin, A.P., Baal, G.C.M. van, Beijsterveldt, C.E.M. van, Boomsma, D.I., Geus, E.J.C. de, Grant, J.   +5 more
core   +2 more sources

2D association and integrative omics analysis in rice provides systems biology view in trait analysis. [PDF]

, 2018
The interactions among genes and between genes and environment contribute significantly to the phenotypic variation of complex traits and may be possible explanations for missing heritability.
Dai, Xinbin, Xu, Shizhong, Zhang, Wenchao, Zhao, Patrick X   +3 more
core   +2 more sources

Animal models with group-specific additive genetic variances: extending genetic group models

Genetics Selection Evolution, 2019
Background The animal model is a key tool in quantitative genetics and has been used extensively to estimate fundamental parameters, such as additive genetic variance or heritability.
Stefanie Muff, Alina K. Niskanen, Dilan Saatoglu, Lukas F. Keller, Henrik Jensen   +4 more
doaj   +1 more source

Sex-specific genetic influence on thyroid-stimulating hormone and free thyroxine levels, and interactions between measurements: KNHANES 2013-2015. [PDF]

PLoS ONE, 2018
BACKGROUND:Although a wide range of genetic influences on thyroid-stimulating hormone (TSH) and free thyroxine (fT4) levels have been reported, sex differences in the genetic influences have not been well described. METHODS:We assessed TSH and fT4 levels
Young Ki Lee, Dong Yeob Shin, Hyejung Shin, Eun Jig Lee   +3 more
doaj   +1 more source

Clarifying the relationship between average excesses and average effects of allele substitutions

Frontiers in Genetics, 2012
Fisher’s concepts of average effects and average excesses are at the core of the quantitative genetics theory. Their meaning and relationship have regularly been discussed and clarified.
Jose M eÁlvarez-Castro, Rong-Cai eYang, Rong-Cai eYang   +2 more
doaj   +1 more source