Results 41 to 50 of about 8,139,164 (377)

Ironing out the details: Untangling dietary iron and genetic background in diabetes [PDF]

open access: yes, 2018
The search for genetic risk factors in type-II diabetes has been hindered by a failure to consider dietary variables. Dietary nutrients impact metabolic disease risk and severity and are essential to maintaining metabolic health.
Lawson, Heather A, Miranda, Mario A
core   +2 more sources

Translational regulation contributes to the elevated CO2 response in two Solanum species. [PDF]

open access: yes, 2020
Understanding the impact of elevated CO2 (eCO2 ) in global agriculture is important given climate change projections. Breeding climate-resilient crops depends on genetic variation within naturally varying populations.
Brady, Siobhan M   +6 more
core   +2 more sources

Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

open access: yesNature Biotechnology, 2017
Droplet single-cell RNA-sequencing (dscRNA-seq) has enabled rapid, massively parallel profiling of transcriptomes. However, assessing differential expression across multiple individuals has been hampered by inefficient sample processing and technical ...
H. Kang   +15 more
semanticscholar   +1 more source

Visualizing genetic constraints [PDF]

open access: yes, 2013
Principal Components Analysis (PCA) is a common way to study the sources of variation in a high-dimensional data set. Typically, the leading principal components are used to understand the variation in the data or to reduce the dimension of the data for ...
Gaydos, Travis L.   +6 more
core   +3 more sources

Assessment of Genetic Diversity and Conservation in South African Indigenous Goat Ecotypes: A Review

open access: yesAnimals, 2022
Goats were amongst the first livestock to be domesticated more than 10,000 years ago for their meat, milk, skin, and fiber. They were introduced to Southern Africa by migrating nations from Central Africa to the south.
Aletta Matshidiso Magoro   +3 more
doaj   +1 more source

Considering adaptive genetic variation in climate change vulnerability assessment reduces species range loss projections

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Forecasts of species vulnerability and extinction risk under future climate change commonly ignore local adaptations despite their importance for determining the potential of populations to respond to future changes.
O. Razgour   +9 more
semanticscholar   +1 more source

The Genetic Basis of Mutation Rate Variation in Yeast. [PDF]

open access: yes, 2018
Mutations are the root source of genetic variation and underlie the process of evolution. Although the rates at which mutations occur vary considerably between species, little is known about differences within species, or the genetic and molecular basis ...
Bloom, Joshua S   +2 more
core   +1 more source

Genetic variation in Cumbrians

open access: yesAnnals of Human Biology, 1981
Regional variation in the genetic constitution of the Cumbrian population is demonstrated in a survey of blood groups, red cell enzymes, and secretor status in a large sample of schoolchildren. In particular, the south and centre appear to be distinct from the remainder of Cumbria, but in different directions. The features of the central Lake District,
R.J. Mitchell   +3 more
openaire   +3 more sources

The Stabilizing Effect Of Intraspecific Genetic Variation On Population Dynamics In Novel And Ancestral Habitats [PDF]

open access: yes, 2009
Recent studies show that intraspecific genetic variation in asexual species may have large effects on community and ecosystem functions, increasing their stability, productivity, and species richness.
Agashe, Deepa
core   +1 more source

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

open access: yesNature Genetics, 2008
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem of unknown etiology that varies in prevalence among ancestry groups. To identify genetic variants contributing to differences in hepatic fat content, we carried out a genome-wide ...
S. Romeo   +8 more
semanticscholar   +1 more source

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