Results 51 to 60 of about 1,970,763 (233)
The mechanisms underlying heritable phenotypic divergence associated with adaptation in response to environmental stresses may involve both genetic and epigenetic variations.
Tian Qiu+3 more
doaj +1 more source
From genetic variation to precision medicine
Genetics has been an important tool for discovering new aspects of biology across life. In humans, there is growing momentum behind the application of this knowledge to drive innovation in clinical care, most notably through developments in precision ...
Panagiotis I. Sergouniotis+2 more
doaj +1 more source
Genetic Risk and Atrial Fibrillation in Patients with Heart Failure [PDF]
Aims: To study the association between an atrial fibrillation (AF) genetic risk score with prevalent AF and all-cause mortality in patients with heart failure.
Anker, Stefan D.+22 more
core +3 more sources
Are current ecological restoration practices capturing natural levels of genetic diversity? A New Zealand case study using AFLP and ISSR data from mahoe (Melicytus ramiflorus) [PDF]
Sourcing plant species of local provenance (eco-sourcing) has become standard practice in plant community restoration projects. Along with established ecological restoration practices, knowledge of genetic variation in existing and restored forest ...
Clarke, Andrew C.+4 more
core +2 more sources
Thymallus sp. is a native fish species distributed in the Irtysh River Basin in China. Unfortunately, environmental damage and overfishing have led to a significant decline in Arctic grayling resources, pushing them towards endangerment.
Kai Ma+8 more
doaj +1 more source
Estimated six per cent loss of genetic variation in wild populations since the industrial revolution
Genetic variation is fundamental to population fitness and adaptation to environmental change. Human activities are driving declines in many wild populations and could have similar effects on genetic variation.
Deborah M. Leigh+3 more
doaj +1 more source
Analysis of structural variation among inbred mouse strains
Background ‘Long read’ sequencing methods have been used to identify previously uncharacterized structural variants that cause human genetic diseases.
Ahmed Arslan+10 more
doaj +1 more source
The mapping between genotype and phenotype is encoded in the complex web of epistatic interaction between genetic loci. In this rugged fitness landscape, recombination processes, which tend to increase variation in the population, compete with selection ...
A. Hartmann+18 more
core +1 more source
Genetic Variation in the Response to Vaccination
Vaccines are the most powerful means to prevent and diminish the burden of infectious disease. However, there are limitations to their use: vaccines are not yet available for all infectious diseases (including human immunodeficiency virus and respiratory syncytial virus), they sometimes lack efficacy, the response to vaccination is limited by maternal ...
Kimman, TG+2 more
openaire +3 more sources
Semantic variation operators for multidimensional genetic programming
Multidimensional genetic programming represents candidate solutions as sets of programs, and thereby provides an interesting framework for exploiting building block identification. Towards this goal, we investigate the use of machine learning as a way to
Cava William La+7 more
core +1 more source