Results 141 to 150 of about 4,360,463 (355)

Biochemical genetics of blackfly isozymes : II. Genetic variability and differentiation among natural populations of Simulium ochraceum, the vector of onchocerciasis, in Guatemala

, 1987
Takeshi Agatsuma, Kiichi UEMOTO, A. J. Onofre OCHOA   +2 more
openalex   +2 more sources

Novel Design Architecture for Genetic Stability of Recombinant Poliovirus: the Manipulation of G/C Contents and Their Distribution Patterns Increases the Genetic Stability of Inserts in a Poliovirus-Based RPS-Vax Vector System [PDF]

, 2002
Sang‐Gu Lee, Dae-You Kim, Byung‐Hwa Hyun, Yong‐Soo Bae   +3 more
openalex   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Vector for Positive Selection of In-Frame Genetic Sequences [PDF]

BioTechniques, 1997
Hawke, Noel A., Strong, Scott J., Haire, Robert N., Litman, Gary W.   +3 more
openaire   +4 more sources

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

Intracerebral Transplantation and Successful Integration of Astrocytes following Genetic Modification with a High-Capacity Adenoviral Vector [PDF]

, 2002
Stefan Arnhold, Florian Kreppel, S. Kandirali, Doris Lenartz, Franz‐Josef Klinz, Volker Sturm, Stefan Kochanek, Christian Andressen, Klaus Addicks   +8 more
openalex   +1 more source

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

A simple and efficient CRISPR/Cas9 system permits ultra-multiplex genome editing in plants

Crop Journal
The development and maturation of the CRISPR/Cas genome editing system provides a valuable tool for plant functional genomics and genetic improvement.
Suting Wu, Htin Kyaw, Zhijun Tong, Yirong Yang, Zhiwei Wang, Liying Zhang, Lihua Deng, Zhiguo Zhang, Bingguang Xiao, William Paul Quick, Tiegang Lu, Guoying Xiao, Guannan Qin, Xue’an Cui   +13 more
doaj  

996. Hydrodynamics-Mediated Transfection of the Epstein-Barr Virus (EBV)-Based Plasmid (Episomal) Vectors for Genetic Immunization and Gene Therapy [PDF]

, 2002

openalex   +1 more source