3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source
DECOMPOSING THE SIZE EFFECT ON THE ADOPTION OF INNOVATIONS: AGROBIOTECHNOLOGY AND PRECISION FARMING [PDF]
This study contrasts the relationship between farm-size and adoption for two types of innovations, genetically engineered crops and precision farming, controlling for other factors.
Daberkow, Stan G. +2 more
core +1 more source
, 2006 Transgenic Crops describes the basics of genetic modification for agricultural purposes and a brief history of the technology and the governing policies surrounding it.
Jeff Schahczenski, Katherine Adam
core
Studying Lung Cancer Progression: Insights from Genetically Engineered Mouse Models Of Cancer [PDF]
, 2015 Sarah Neidler, Daniel J. Murphy
openalex +1 more source
An engineered genetic circuit for lactose intolerance alleviation [PDF]
, 2021 Mingyue Cheng +16 more
openalex +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Advanced Functional Materials, EarlyView.Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Direct detection of recombinant gene expression by two genetically engineered yeasts in soil on the transcriptional and translational levels [PDF]
, 1995 Christoph C. Tebbe +4 more
openalex +1 more source
Advanced Functional Materials, EarlyView.The first cryo‐EM visualization and quantification of oriented Photosystem I (PSI) on single‐layer graphene is reported. Domain‐specific covalent anchoring of PSI, with the reducing side of the biophotocatalyst toward graphene, promotes three‐fold higher anodic photocurrent generation compared to a randomly physisorbed counterpart. This approach allows
Miriam Izzo +6 more
wiley +1 more source
307 IL12 genetically engineered myeloid cells effectively target the myeloid-enriched tumor and metastatic microenvironment in an immune-competent murine model of osteosarcoma [PDF]
, 2022 Kristin Wessel +4 more
openalex +1 more source
Advanced Functional Materials, EarlyView.This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti +3 more
wiley +1 more source