CAR‐T‐cell products in solid tumors: Progress, challenges, and strategies
Interdisciplinary MedicineT cells engineered to express chimeric antigen receptors (CARs) with specificity toward tumor cells have led to promising outcomes in patients with hematological malignancies. Nevertheless, the application of CAR‐T cell therapy in solid tumors encounters
Kewen Qian +8 more
doaj +1 more source
Recent Advances in Genetically Engineered Microorganisms and their Risks: A Review
International Journal on Food, Agriculture and Natural Resources, 2023 Genetically engineered microorganisms have applications in various domains, such as agriculture, bioscience, healthcare, life sciences, and research. The novel methods of the system Clustered Regularly Interspaced Short Palindromic Repeats associated ...
Jiregna Gari +2 more
doaj +1 more source
Genetically engineered foods: StarLink corn in taco shells [PDF]
, 2002 2 pages.Fact sheet about StarLink genetically-engineered corn getting into the food ...
Genetically Engineered Organisms Public Issues Education Project
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Distributed classifier based on genetically engineered bacterial cell cultures
, 2014 We describe a conceptual design of a distributed classifier formed by a population of genetically engineered microbial cells. The central idea is to create a complex classifier from a population of weak or simple classifiers.
Didovyk, Andriy +5 more
core +2 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Cancer Cell InternationalClear cell renal cell carcinoma (ccRCC) is a globally severe cancer with an unfavorable prognosis. PANoptosis, a form of cell death regulated by PANoptosomes, plays a role in numerous cancer types.
Kangkang Yang +9 more
doaj +1 more source
Genetically engineered foods: in the marketplace [PDF]
, 2002 2 pages.Fact sheet about genetically-engineered foods that are commonly available to ...
Genetically Engineered Organisms Public Issues Education Project
core
A Forward-Design Approach to Increase the Production of Poly-3-Hydroxybutyrate in Genetically Engineered Escherichia coli [PDF]
, 2015 Biopolymers, such as poly-3-hydroxybutyrate (P(3HB)) are produced as a carbon store in an array of organisms and exhibit characteristics which are similar to oil-derived plastics, yet have the added advantages of biodegradability and biocompatibility ...
Bower, I +12 more
core +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Detection of genetically modified plant products by protein strip testing: an evaluation of real-life samples [PDF]
, 2007 The determination of the presence of genetically modified plant material by the detection of expressed genetically engineered proteins using lateral flow protein strip tests has been evaluated in different matrices. The presence of five major genetically
CASI, AL +7 more
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