Results 111 to 120 of about 8,336,560 (363)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Consumer Response to Genetically Modified Foods [PDF]

The consumer trait and characteristic identification, and corresponding relationship to the genetically modified food product's negative reactions was determined from a 354 respondent, 130 item mailed survey.
Mowen, John C., Brant, Molly, Tilley, Daniel S.   +2 more
core  

Generation of Genetically Modified Mice using the CRISPR-Cas9 Genome-Editing System

Cold Spring Harbor Protocols, 2016
Genetically modified mice are extremely valuable tools for studying gene function and human diseases. Although the generation of mice with specific genetic modifications through traditional methods using homologous recombination in embryonic stem (ES ...
Jorge Henao-Mejia, Adam Williams, A. Rongvaux, Judith Stein, C. Hughes, R. Flavell   +5 more
semanticscholar   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

MODELING INTERNATIONAL TRADE IMPACTS OF GENETICALLY MODIFIED WHEAT INTRODUCTIONS [PDF]

Planned introductions of genetically modified crop varieties can be troublesome to model. Estimation of demand and supply equations is not feasible due to lack of data.
DeVuyst, Cheryl Sinn, Koo, Won W., Taylor, Richard D., DeVuyst, Eric A.   +3 more
core  

Guidance on the environmental risk assessment of genetically modified plants

, 2010
This document provides guidance for the environmental risk assessment (ERA) of genetically modified (GM) plants submitted within the framework of Regulation (EC) No.
EFSA Panel on Genetically Modified Organisms (GMO)
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

RNAi-Mediated Silencing of vATPase Subunit E Impairs Larval Development in Plutella xylostella, and Virtual Screening Identifies a Potential Inhibitor

Insects
The diamondback moth (Plutella xylostella) is a devastating global pest of cruciferous crops. This study explores the potential of targeting the vacuolar ATPase subunit E (PxvATPaseE) for its control.
Xuetao Yu, Jinhua Luo, Jiayi Xue, Lin Lu, Pan Deng, Li Zhu, Kang Yang, Xia Wan, Yuhua Wu, Akmal Boboev, Gang Wu, Xiaohong Yan, Chenhui Shen   +12 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Neoclassical consumer theory and genetically modified food [PDF]

Three axioms underpin consumer choice in neoclassical theory: weak order, independence, and continuity. Two of these axioms may not hold, however, for consumers’ choices regarding genetically modified (GM) food.
Kaye-Blake, William
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