Results 121 to 130 of about 8,336,560 (363)

Benefits and costs of biologically contained genetically modified tomatoes and eggplants in Italy and Spain [PDF]

, 2011
In this paper we assess the benefits and costs of introducing biologically contained genetically modified (GM) crops, with an application to the potential introduction of GM tomatoes and eggplants in Italy and Spain.
Wesseler, J.H.H., Groeneveld, R.A., Ansink, E., Wiel, C.C.M., van de   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Does Mandatory Labeling of Genetically Modified Food Grant Consumers the Right to Know? Evidence from an Economic Experiment [PDF]

Opponents of the voluntary labeling scheme for genetically modified (GM) food products often argue that consumers have the ?right to know? and therefore advocate mandatory labeling. In this paper we argue against this line of reasoning.
Sturm, Bodo, Dannenberg, Astrid, Scatasta, Sara   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

OBJECTIVE AND SUBJECTIVE KNOWLEDGE: IMPACTS ON CONSUMER DEMAND FOR GENETICALLY MODIFIED FOODS IN THE UNITED STATES AND THE EUROPEAN UNION [PDF]

In the growing body of literature on consumer acceptance of genetically modified (GM) foods, there are significant differences on the impact of knowledge on acceptance of GM foods.
Valli, Carlotta, Traill, W. Bruce, House, Lisa, Morrow, Bert, Jaeger, Sara, Yee, Wallace M.S., Moore, Melissa, Lusk, Jayson L.   +7 more
core  

Ion homeostasis and coordinated salt tolerance mechanisms in a barley (Hordeum vulgare L.)doubled haploid line

BMC Plant Biology
Salinization poses a significant challenge in agriculture. Identifying salt-tolerant plant germplasm resources and understanding their mechanisms of salt tolerance are crucial for breeding new salt-tolerant plant varieties.
Hongwei Xu, Hui Chen, Nigel G. Halford, RugenXu, Ting He, Bangwei Yang, Longhua Zhou, HuiminGuo, ChenghongLiu   +8 more
doaj   +1 more source

Generic Workflow of a Highly Effective and Easy Anther Culture Method for Both Japonica and Indica Rice

Plants
As one of the most important staple crops in the world, rice plays a pivotal role in world food security. The creation of doubled haploids based on anther culture is an important technology for rice breeding.
Guimei Guo, Shisen Liu, Shuwei Zhang, Linian Yang, Yingjie Zong, Nigel G. Halford, Ting He, Runhong Gao, Zhenzhu Guo, Longhua Zhou, Chenghong Liu, Shujun Wu, Zhiwei Chen   +12 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

CONSUMER VALUATION OF GENETICALLY MODIFIED FOODS AND THE EFFECT OF INFORMATION BIAS [PDF]

Bid prices were elicited for standard-label cookies, muffins, and potato chips and those identified as not including genetically modified (GM) ingredients using an experimental auction.
Schuck, Eric C., Vanwechel, Tamara, Wachenheim, Cheryl J., Lambert, David K.   +3 more
core