Results 301 to 310 of about 8,336,560 (363)
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Genetic Modifiers in Hemoglobinopathies
Current Molecular Medicine, 2008Hereditary anemias show considerable variation in their clinical presentation. In some cases, the causes of these variations are easily apparent. In thalassemia (or in HbE/thalassemia), genetic variation is primarily caused by the severity of the thalassemia mutation.
Deborah, Rund, Suthat, Fucharoen
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Genetically modified allergens
Immunology and Allergy Clinics of North America, 2004For more than 90 years, allergen-specific immunotherapy, the only causative allergy treatment, has remained basically unchanged. The development of molecular biology techniques has led to the preparation of individual recombinant allergens from the most important allergen sources.
Verena, Niederberger, Rudolf, Valenta
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The Ecology of Genetically Modified Mosquitoes
Science, 2002Ecological and population biology issues constitute serious challenges to the application of genetically modified mosquitos (GMM) for disease control.
Scott, T.W. +3 more
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Genetically modified food enzymes: a review
Current Opinion in Food Science, 2019Natural food enzymes often have limitations in sophisticated and extreme food processing conditions. Genetically modified enzymes are designed to improve or alter the enzymological properties and/or increase purity and yield of expression, changes which ...
Yi Zhang, T. Geary, B. Simpson
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Genetic modifiers of Huntington's disease
Movement Disorders, 2014AbstractHuntington's disease (HD) is a devastating neurodegenerative disorder that directly affects more than 1 in 10,000 persons in Western societies but, as a family disorder with a long, costly, debilitating course, it has an indirect impact on a far greater proportion of the population.
James F, Gusella +2 more
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Genetically modified mice and cognition
Current Opinion in Neurobiology, 1998Cognition in transgenic and knockout mice is preferentially assessed by spatial learning in the Morris water maze. Awareness is growing, however, that the putative cognitive deficits observed using such a paradigm may be biased by the genetic background and behavioral peculiarities of the specific animals used.
Lipp HP, Wolfer DP
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Genetically modified animals and immunodeficiency
Current Opinion in Immunology, 1993Mouse strains with defined genetic defects engineered by the method of targeted gene disruption and homologous recombination have furthered our understanding of immune functions at the single gene level. More importantly, these mutant 'gene knockout' mice are powerful in vivo tools to dissect the complex mechanisms of lymphocyte development and ...
R S, Yeung, J, Penninger, T W, Mak
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Patents for genetically modified animals
Journal of Animal Science, 1993Should genetically engineered animals be patented? This issue has been one of the most contentious as lawmakers have grappled with how best to protect intellectual property. Since the 1980 case of Diamond v. Chakrabarty, in which the U.S. Supreme Court ruled that a living microorganism is patentable, the U.S.
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Spatial Efficiency of Genetically Modified and Non-Genetically Modified Crops
Strategic Behavior and the Environment, 2015When GM (genetically modified) and non-GM crops coexist, not all of the latter can be sold as GM-free crops as some of them will likely be contaminated by GM crops. The choice of producing non-GM crops will consequently depend on the surrounding crops. We therefore analyze the spatial distribution of GM and non-GM crops.
Ambec, Stefan +2 more
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