Results 51 to 60 of about 8,336,560 (363)

Microbe and plant assisted-remediation of organic xenobiotics and its enhancement by genetically modified organisms and recombinant technology: A review.

Science of the Total Environment, 2018
Environmental problems such as the deterioration of groundwater quality, soil degradation and various threats to human, animal and ecosystem health are closely related to the presence of high concentrations of organic xenobiotics in the environment ...
Imran Hussain, Gajender Aleti, R. Naidu, M. Puschenreiter, Q. Mahmood, M. Rahman, Fang Wang, S. Shaheen, J. Syed, T. Reichenauer   +9 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Guidance on allergenicity assessment of genetically modified plants

EFSA journal. European Food Safety Authority, 2017
This document provides supplementary guidance on specific topics for the allergenicity risk assessment of genetically modified plants. In particular, it supplements general recommendations outlined in previous EFSA GMO Panel guidelines and Implementing ...
H. Naegeli, A. E. Birch, J. Casacuberta, A. de Schrijver, M. Gralak, P. Guerche, Huw Jones, B. Manachini, A. Messéan, E. Nielsen, F. Nogué, C. Robaglia, N. Rostoks, J. Sweet, C. Tebbe, F. Visioli, J. Wal, P. Eigenmann, M. Epstein, K. Hoffmann-Sommergruber, F. Koning, M. Løvik, C. Mills, F. Moreno, H. van Loveren, R. Selb, Antonio Fernández Dumont   +26 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Qualitative and Quantitative Detection of CRISPR-Associated Cas Gene in Gene-Edited Foods

Foods, 2023
Effective regulation of gene-edited products and resolution of public concerns are the prerequisites for the industrialization of gene-edited crops and their derived foods.
Lin Ding, Xiaoli Xu, Xiaofu Wang, Xiaoyun Chen, Yuwen Lu, Junfeng Xu, Cheng Peng   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Allicin Regulates Energy Homeostasis through Brown Adipose Tissue

iScience, 2020
Summary: Brown adipose tissue (BAT) is a promising potential therapeutic target for the treatment of obesity and related metabolic diseases. Allicin, a natural product in garlic, has multiple biological and pharmacological functions. However, the role of
Chuanhai Zhang, Xiaoyun He, Yao Sheng, Jia Xu, Cui Yang, Shujuan Zheng, Junyu Liu, Haoyu Li, Jianbing Ge, Minglan Yang, Baiqiang Zhai, Wentao Xu, Yunbo Luo, Kunlun Huang   +13 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

SUPER WOMAN 2 (SPW2) maintains organ identity in spikelets by inhibiting the expression of floral homeotic genes OsMADS3, OsMADS58, OsMADS13, and DROOPING LEAF

Journal of Integrative Agriculture
Flower organ identity in rice is mainly determined by the A-, B-, C- and E-class genes, with the majority encoding MADS-box transcription factors. However, few studies have investigated how the expression of these floral organ identity genes is regulated
Hui Zhuang, Jinsong Lan, Qiuni Yang, Xiaoyu Zhao, Yuhuan Li, Jingya Zhi, Yalin Shen, Guanghua He, Yunfeng Li   +8 more
doaj   +1 more source