Results 181 to 190 of about 54,452 (291)

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Effects of genetically modified maize expressing Cry1Ab and EPSPS proteins on Japanese quail. [PDF]

Poult Sci, 2021
Zhang L, Shen W, Fang Z, Liu B.
europepmc   +1 more source

Inventory of observed unexpected environmental effects of genetically modified crops [PDF]

In general, it can be concluded that very few clearly unexpected effects were observed during the large scale post-release growing of herbicide-tolerant crops and Bt crops.
Brink, L., van den, Bus, C.B., Franke, A.C., Groten, J.A.M., Lotz, L.A.P., Timmer, R.D., Wiel, C.C.M., van de   +6 more
core   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Assessment of the 2019 post-market environmental monitoring report on the cultivation of genetically modified maize MON 810 in the EU. [PDF]

EFSA J, 2021
European Food Safety Authority (EFSA), Álvarez F, Messéan A, Streissl F.   +3 more
europepmc   +1 more source

Post-Moratorium EU Regulation of Genetically Modified Products: Triffid Flax [PDF]

The regulatory regime for contamination permits the imposition of import bans with neither a scientific justification nor a risk assessment. No scientific assessment of Triffid flax was done prior to the import ban. The import regime put in place to deal
Kerr, William A., Viju, Crina, Yeung, May T.   +2 more
core   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Development of a duplex chamber digital PCR to quantify twelve genetically modified maize events. [PDF]

GM Crops Food
Kim EH, Cho YS, Kim B, Yoo Y, Lee JI, Kim YS, Park TS.   +6 more
europepmc   +1 more source

Untargeted Proteomics-Based Approach to Investigate Unintended Changes in Genetically Modified Maize for Environmental Risk Assessment Purpose. [PDF]

Front Toxicol, 2021
Zanon Agapito-Tenfen S, Guerra MP, Nodari RO, Wikmark OG.   +3 more
europepmc   +1 more source

Post-Moratorium EU Regulation of Genetically Modified Products: Trade Concerns [PDF]

Trade in genetically modified (GM) products remains a major issue in agricultural trade policy. In particular, the European Union has sought to deny market access to GM-products.
Kerr, William A., Viju, Crina, Yeung, May T.   +2 more
core   +1 more source