Results 71 to 80 of about 2,194,487 (258)

Oral delivery of dsRNA by microbes: Beyond pest control

Communicative & Integrative Biology, 2016
RNA interference (RNAi) by oral delivery of dsRNA in insects has great potential as a tool for integrated pest management (IPM), especially with respect to addressing the need to reduce off-target effect and slow down resistance development to chemical ...
Antoine Abrieux, Joanna C. Chiu
doaj   +1 more source

GENETICALLY MODIFIED MICRO-ORGANISMS: THE EU REGULATORY FRAMEWORK AND THE NEW DIRECTIVE 2009/41/EC ON THE CONTAINED USE

Chemical Engineering Transactions, 2010
preview not available - see full-text PDF article.
G. Fontana
doaj   +1 more source

Introducing Genetically Modified Plants: Now or Later - An Option Value Approach [PDF]

Using market data, we have estimated the quasi option value of delaying to grow genetically modified corn and soybeans in Europe. We find that the current quasi option value of growing genetically modified soybeans and corn in Europe is high.
Brimi, Live, Romstad, Eirik, Ljorerud, Urda   +2 more
core  

Design of a Novel Diamine Biosensor to Guide the Engineering of Escherichia coli for Cadaverine Overproduction

Advanced Science, EarlyView.
A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng, Getao Liu, Ding Ma, Jiaxiang Yuan, Xinyi Zhang, Weihao Wang, Chen Ma, Yang Liao, Siyuan Gao, Lei Qin, Jiao Feng, Sheng Xu, Xin Wang, Kequan Chen   +13 more
wiley   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

Angewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa Ponomareva, Isaline Fagon, Leslie Fève, Kendall Paige, Courtney L. Brown, Nora Schwartz, Jacob Hecht, Jennifer Nguyen, Jon S. Thorson, Jacques Neefjes, S. Eric Nybo, Khaled A. Shaaban, Mikko Metsä‐Ketelä   +15 more
wiley   +2 more sources

Guidance on the characterisation of microorganisms in support of the risk assessment of products used in the food chain

EFSA Journal
This document provides guidance to assist in the preparation of applications for regulated products to be used in the food chain containing, made from or produced by using microorganisms, genetically modified or not, that are subject to risk assessment ...
EFSA Scientific Committee, Susanne Hougaard Bennekou, Ana Allende, Angela Bearth, Josep Casacuberta, Laurence Castle, Tamara Coja, Amélie Crépet, Thorhallur Ingi Halldorsson, Ron Hoogenboom, Pikka Jokelainen, Helle Katrine Knutsen, Claude Lambré, Søren Saxmose Nielsen, Dominique Turck, Antonio Vicent Civera, Roberto Edoardo Villa, Holger Zorn, Margarita Aguilera Gómez, Stéphane Brétagne, Henrik Christensen, Pier Sandro Cocconcelli, Lieve Herman, Miguel Prieto‐Maradona, Baltasar Mayo, Carmen Peláez, Maria Saarela, José Sánchez Serrano, Laurence Vernis, Andrey Yurkov, Jaime Aguilera, Montserrat Anguita, Nicole Bozzi Cionci, Rosella Brozzi, Sandra Correia, Yolanda García‐Cazorla, Frédérique Istace, Elisa Pettenati, Joana Revez, Reinhilde Schoonjans, Piera Valeri, Boet Glandorf   +41 more
doaj   +1 more source

Genetically modified maize: exploring consumer acceptance [PDF]

Recent EU regulations have imposed mandatory labelling of all food products that consist of or contain genetically modified organisms (GMOs). Labelling should state that "this product contains genetically modified organisms".
Sinanoglou, Vasilia, Sakellaris, George, Batrinou, Anthimia M., Gogkou, Antigoni   +3 more
core  

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

Advanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen, Jianhua Lv, Yuanqing Cai, Xuhui Yuan, Hongxin Hu, Jiayu Li, Yiming Lin, Hongyan Li, Lan Lin, Huangfeng Lin, Chaofan Zhang, Qijin Wang, Ying Huang, Zida Huang, Wenbo Li, Susheng Niu, Jianhua Lin, Bin Yang, Xinyu Fang, Wenming Zhang   +19 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +2 more sources

Decoding oxidative stress regulation in food crops exposed to heavy metals: interdisciplinary strategies for sustainable mitigation

Discover Sustainability
The urgent need to address heavy metal (HM) toxicity in agriculture and its impact on human health calls for innovative solutions such as phyto-remediation, microbial-remediation and the development of transgenic plants to mitigate HM accumulation in ...
Nitika Thakur, Pooja Sharma, Nidhi Negi, Nittan Sharma, Parul Sharma   +4 more
doaj   +1 more source