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Applications and limitations of genetically modified mouse models in drug discovery and development.
Current drug metabolism, 2008Genetically modified mouse models in which a specific gene is removed or replaced have proven to be powerful tools for identification/validation of target gene and scientific understanding of molecular mechanisms underlying drug-induced toxicity through ...
J. Lin
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Axon regeneration after spinal cord injury: Insight from genetically modified mouse models
Restorative Neurology and Neuroscience, 2008The use of genetically modified mice to study axon regeneration after spinal cord injury has served as a useful in vivo model for both loss-of-function and gain-of-function analysis of candidate proteins.
Jae K. Lee, B. Zheng
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Regression of atherosclerosis: lessons learned from genetically modified mouse models
Current Opinion in Lipidology, 2018A. Burke, M. Huff
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Modeling RASopathies with Genetically Modified Mouse Models.
Methods in molecular biology, 2017Isabel Hernández-Porras, C. Guerra
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PROBABILITY LEARNING IN GENETICALLY MODIFIED MOUSE LINES
, 2018A. Tkachenko+3 more
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Genetically Modified Mouse Models of Adamantinomatous Craniopharyngioma
, 2017C. Andoniadou, J. MartÃnez-Barbera
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Genetically Modified Mouse Models for Biomarker Discovery and Preclinical Drug Testing
Clinical Cancer Research, 2012R. Kucherlapati
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