Results 291 to 300 of about 505,318 (323)

Preclinical Assessment of Living Therapeutic Materials: State-of-Art and Challenges. [PDF]

ACS Biomater Sci Eng
Desai K, Mekontso J, Deshpande K, Trujillo S.   +3 more
europepmc   +1 more source

Paromomycin is a more effective selection agent than kanamycin in Arabidopsis harboring the neomycin phosphotransferase II transgene. [PDF]

PLoS One
Goodman CP, Padgett VN, Evans ER, von Arnim AG.   +3 more
europepmc   +1 more source

Hypoplastic left heart syndrome-a scoping review. [PDF]

Transl Pediatr
Sergi CM.
europepmc   +1 more source

Engineering mice for female-biased progeny without impacting genetic integrity and litter size

Qimron U, Yosef I, Mahata T, Xie X, Chen Y, Bar-Joseph H, Sun Q, Shalgi R, Munitz A, Gerlic M.   +9 more
europepmc   +1 more source

Miniature endoscope for high resolution electrophysiological recordings from the colon of live mice

Sobolewski A, Planchette A, Wójcicki K, Cabara Y, Hibberd T, Travis L, Spencer N, Gora M.   +7 more
europepmc   +1 more source

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Genetically modified mouse models for pharmacogenomic research

Nature Reviews Genetics, 2004
It is now evident that differences in the DNA sequence of genes involved with drug action can lead to interindividual differences in effectiveness and adverse reactions to therapeutic drugs. Pharmacogenomics raises the possibility that drug discovery and patient management could move from a 'one drug fits all' approach to one in which therapy is ...
S. Liggett
semanticscholar   +3 more sources

In vivo Studies of the Genetically Modified Mouse Kidney

Nephron Physiology, 2003
Gene-targeted mice provide a powerful approach to study the physiological and pathophysiological role of a given protein in kidney function and can give insights on the functional importance of these proteins under in vivo conditions as well as on the potential compensating mechanisms in their absence.
V. Vallon
semanticscholar   +4 more sources

Genetically modified mouse models in cancer studies

Clinical and Translational Oncology, 2008
Genetically modified animals represent a resource of immense potential for cancer research. Classically, genetic modifications in mice were obtained through selected breeding experiments or treatments with powerful carcinogens capable of inducing random mutagenesis.
Javier Santos, P. Fernández-Navarro, M. Villa-Morales, Laura González-Sánchez, J. Fernández-Piqueras   +4 more
semanticscholar   +4 more sources

Genetically modified mouse models for premature ovarian failure (POF)

Molecular and Cellular Endocrinology, 2010
Premature ovarian failure (POF) is a complex disorder that affects approximately 1% of women. POF is characterized by the depletion of functional ovarian follicles before the age of 40 years, and clinically, patients may present with primary amenorrhea or secondary amenorrhea.
K. Jagarlamudi, P. Reddy, D. Adhikari, Kui Liu   +3 more
semanticscholar   +3 more sources