Results 291 to 300 of about 277,970 (322)

Genetic Modifiers of Cardiac Development 22q11DS Mouse Models

The FASEB Journal, 2016
Over 70% of patients with 22q11.2 Deletion Syndrome (22q11DS) have congenital heart defects. The prevalence and severity of these defects make it critical for us to strive to understand the underlying mechanism of the syndrome by elucidating the gene pathways that are involved in heart development, as their disruption may lead to ...
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Genetically modified mouse models to investigate thyroid development, function and growth

Best Practice & Research Clinical Endocrinology & Metabolism, 2018
The thyroid gland produces thyroid hormones (TH), which are essential regulators for growth, development and metabolism. The thyroid is mainly controlled by the thyroid-stimulating hormone (TSH) that binds to its receptor (TSHR) on thyrocytes and mediates its action via different G protein-mediated signaling pathways.
Kero Andreina, Löf Christoffer, Kero Jukka, Patyra Konrad, Kero Andreina, Kero Jukka   +5 more
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Genetic modifiers that aggravate the neurological phenotype of the wobbler mouse

Neuroreport, 2002
The autosomal recessive mutation wobbler of the mouse (phenotype WR; genotype wr/wr) causes muscular atrophy due to motoneuron degeneration with 100% penetrance on the standard Mus musculus laboratorius C57BL/6J background. In inter- and backcrosses with M. m.
Ulbrich, Michael, Schmidt, Volker, Ronsiek, Melanie, Mussmann, Anke, Bartsch, Jörg, Augustin, Martin, Jockusch, Harald, Schmitt-John, Thomas   +7 more
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Genetically Modified Mouse Models for Biomarker Discovery and Preclinical Drug Testing

Clinical Cancer Research, 2012
Abstract The ability to grow pluripotent mouse embryonic stem cells in culture, and to introduce precise genetic modifications into those cells through gene targeting, has greatly facilitated the generation of mouse models of human disease. This technology is playing a particularly important role in cancer research.
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Probability Learning In Genetically Modified Mouse Lines

Laboratornye Zhivotnye dlya nauchnych issledovanii (Laboratory Animals for Science), 2018
A.A. Tkachenko, S.V. Ranneva, L.V. Loskutova, T.V. Lipina   +3 more
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Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023

exaly  

Genetically Modified NAT Mouse Models

2018
Kim S. Sugamori, Denis M. Grant
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Genetically modified mouse as an experimental model in biomedicine

2001
no ...
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The role of the microbiome in cancer development and therapy

Ca-A Cancer Journal for Clinicians, 2017
Aadra P Bhatt, Matthew R Redinbo
exaly  

The impact of comorbidity on cancer and its treatment

Ca-A Cancer Journal for Clinicians, 2016
Diana Sarfati, Bogda Koczwara
exaly