Results 91 to 100 of about 277,869 (310)

CRISPR-Based Biosensing for Genetically Modified Organism Detection: Current Applications and Future Perspectives

Agronomy
The rapid global expansion of genetically modified (GM) crops requires fast, on-site detection methods. Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated (CRISPR/Cas) systems offer a promising platform for decentralized GM ...
Jingying Yan, Yuan Zhou, Junhui Sun, Sanling Wu, Zhongjie Ding, Liang Ni, Jianjun Wang   +6 more
doaj   +1 more source

Screening of Colombian soybean genotypes for Agrobacterium mediated genetic transformation conferring tolerance to Glyphosate

Agronomía Colombiana, 2018
Soybean is a very important crop worldwide due to its multiple uses as raw material for industry and to its high nutritional value. Colombia consumes a large amount of imported soybean because domestic production does not supply demand. There are soybean
Alejandro Chaparro Giraldo, Adriana Carolina Rojas, Silvio Alejandro Lopez Pazos   +2 more
doaj   +1 more source

Detection Methods of Genetically Modified Organisms (GMOS): Review

, 2023
M Gidi
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Identification of genetically modified organisms in foods of plant origin as a way to control health risks for consumers [PDF]

, 2022
G.F. Mukhammadiyeva, D.O. Karimov, E.R. Shaikhlislamova, A.B. Bakirov, E.R. Kudoyarov, Yana V. Valova, R.A. Daukaev, E.F. Repina   +7 more
openalex   +1 more source

Genetically modified organisms (GMOs) in Pakistan

, 2012
Biotechnology in the recent years has emerged as a powerful medium for socio-economic development. A wide array of biotechnological techniques is being developed.
Waris Ali Gabol, Aleem Ahmed, H. Bux, K. Ahmed, A. Mahar, Shafiullah Laghari   +5 more
semanticscholar   +1 more source

3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research

Advanced Functional Materials, EarlyView.
A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram, Majd Machour, Janette Zavin, Roy Meretzki, Reut Lev‐Ari, Shulamit Levenberg   +5 more
wiley   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Genetically modified organisms (GMO) in opinions completing secondary schools in Lublin [PDF]

, 2016
Stanisław Lachowski, Magdalena Florek-Łuszczki, Anna Jurkiewicz, Jarosław Chmielewski, Ilona Żeber–Dzikowska   +4 more
openalex   +1 more source