Results 301 to 310 of about 439,037 (382)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

open access: yesAdvanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou   +10 more
wiley   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Assessment of genetically modified soybean MON 87769 for renewal authorisation under Regulation (EC) No 1829/2003 (dossier GMFF-2023-21253). [PDF]

open access: yesEFSA J
EFSA Panel on Genetically Modified Organisms (GMO)   +23 more
europepmc   +1 more source

Impact of herbicide-resistant genetically modified rapeseed on gut bacterial diversity of <i>Eisenia fetida</i>. [PDF]

open access: yesGM Crops Food
Jang YJ   +7 more
europepmc   +1 more source

Assessment of genetically modified soybean MON 87705 for renewal authorisation under Regulation (EC) No 1829/2003 (application GMFF-2023-21236). [PDF]

open access: yesEFSA J
EFSA Panel on Genetically Modified Organisms (GMO)   +24 more
europepmc   +1 more source

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