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Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Synthetic biology and genome engineering in support of human, agricultural, and environmental security. [PDF]

Front Bioeng Biotechnol
Chapman CR, Trolle J, Wawrzyniak DD, Boeke JD, Brosh R.   +4 more
europepmc   +1 more source

Safety evaluation of a second extension of use of the food enzyme thermolysin from the non-genetically modified <i>Anoxybacillus caldiproteolyticus</i> strain AE-TP. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Cavanna D, Liu Y.   +14 more
europepmc   +1 more source

Safety evaluation of an extension of use of the food enzyme leucyl aminopeptidase from the genetically modified <i>Aspergillus oryzae</i> strain NZYM-BU. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Bonino I, Cavanna D, Liu Y.   +15 more
europepmc   +1 more source

Safety evaluation of an extension of use of the food enzyme chymotrypsin from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-RH. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Rosell AF, Cavanna D, Liu Y.   +15 more
europepmc   +1 more source

Exploring the dynamics of symbiont Enterobacter aerogenes expressing Cry1Ac for potential biocontrol of Helicoverpa armigera. [PDF]

World J Microbiol Biotechnol
Ojha A, Usman M.
europepmc   +1 more source

Gene Flow and Hybridization Potential Between GM/NGT Crops and Conventional Varieties or Wild Relatives: A Scoping Literature Review with Emphasis on Oilseed Rape (<i>Brassica napus</i> L.) and Potato (<i>Solanum tuberosum</i> L.). [PDF]

BioTech (Basel)
Grantina-Ievina L, Rostoks N.
europepmc   +1 more source

GENETICALLY MODIFIED PEST-PROTECTED PLANTS: SCIENCE AND REGULATION

, 2000
National Research Council (United States). Board on Agriculture and Natural Resources. Committee on Genetically Modified Pest-Protected Plants
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Are Genetically Modified Plants Useful and Safe?

IUBMB Life, 2005
AbstractSo far, plants have been genetically modified essentially to achieve resistance to herbicides, or to pathogens (mainly insects, or viruses), but resistance to abiotic stresses (such as cold, heat, drought, or salt) is also being studied. Genetically modified (GM) plants with improved nutritional qualities have more recently been developed, such
openaire   +2 more sources