Results 21 to 30 of about 291,455 (281)

New approaches to combat Porphyromonas gingivalis biofilms

Journal of Oral Microbiology, 2017
In nature, bacteria predominantly reside in structured, surface-attached communities embedded in a self-produced, extracellular matrix. These so-called biofilms play an important role in the development and pathogenesis of many infections, as they are ...
Evelien Gerits, Natalie Verstraeten, Jan Michiels   +2 more
doaj   +1 more source

Elevated acetate kinase (ackA) gene expression, activity, and biofilm formation observed in methicillin-resistant strains of Staphylococcus aureus (MRSA)

Journal of Genetic Engineering and Biotechnology, 2023
Background Staphylococcus aureus spreads its infections through biofilms. This usually happens in the stationary phase of S. aureus growth where it utilizes accumulated acetate as a carbon source via the phosphotrans-acetylase-acetate kinase (Pta-Ack ...
Subbarayudu Suthi, A. Mounika, Venkata Gurunadha Krishna Sarma Potukuchi   +2 more
doaj   +1 more source

Evolutionary biology for the 21st century [PDF]

, 2013
New theoretical and conceptual frameworks are required for evolutionary biology to capitalize on the wealth of data now becoming available from the study of genomes, phenotypes, and organisms - including humans - in their natural environments.Molecular ...
Arnold, Stevan J., Bejerano, Gill, Brodie, E. D., Hibbett, David, Hoekstra, Hopi E., Losos, Jonathan B., Mindell, David P., Monteiro, Antónia, Moritz, Craig, Orr, H. Allen, Petrov, Dmitri A., Renner, Susanne S., Ricklefs, Robert E., Soltis, Pamela S., Turner, Thomas L.   +14 more
core   +5 more sources

Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy

Nature Communications, 2020
Bacterial biofilms rely on shared extracellular polymeric substances (EPS) and are often highly tolerant to antibiotics. Here, the authors show in in vitro experiments that Salmonella does not evolve resistance to EPS inhibition because such strains are ...
Lise Dieltjens, Kenny Appermans, Maries Lissens, Bram Lories, Wook Kim, Erik V. Van der Eycken, Kevin R. Foster, Hans P. Steenackers   +7 more
doaj   +1 more source

Variable responses of human and non-human primate gut microbiomes to a Western diet [PDF]

, 2015
BACKGROUND: The human gut microbiota interacts closely with human diet and physiology. To better understand the mechanisms behind this relationship, gut microbiome research relies on complementing human studies with manipulations of animal models ...
Amato, Katherine R., Cerda, Gabriela, Cramer, Jennifer Danzy, Gomez, Andres, Knight, Rob, Leigh, Steven R., Miller, Margret E. Berg, Nelson, Karen E., Schmitt, Christopher A., Stumpf, Rebecca M., Turner, Trudy R., White, Bryan A., Wilson, Brenda A., Yeoman, Carl J.   +13 more
core   +5 more sources

Effects of preservation method on canine (Canis lupus familiaris) fecal microbiota. [PDF]

, 2018
Studies involving gut microbiome analysis play an increasing role in the evaluation of health and disease in humans and animals alike. Fecal sampling methods for DNA preservation in laboratory, clinical, and field settings can greatly influence ...
Eisen, Jonathan A, Ganz, Holly H, Horng, Katti R, Marks, Stanley L   +3 more
core   +2 more sources

A Decade of Plague in Mahajanga, Madagascar: Insights into the Global Maritime Spread of Pandemic Plague

mBio, 2013
A cluster of human plague cases occurred in the seaport city of Mahajanga, Madagascar, from 1991 to 1999 following 62 years with no evidence of plague, which offered insights into plague pathogen dynamics in an urban environment.
Amy J. Vogler, Fabien Chan, Roxanne Nottingham, Genevieve Andersen, Kevin Drees, Stephen M. Beckstrom-Sternberg, David M. Wagner, Suzanne Chanteau, Paul Keim   +8 more
doaj   +1 more source

Enhancement of feather degrading keratinase of Streptomyces swerraensis KN23, applying mutagenesis and statistical optimization to improve keratinase activity

BMC Microbiology, 2023
In this study, 25 actinomyces isolates were obtained from 10 different poultry farms and tested for their keratinase activity. The isolate with the highest keratinase activity was identified through molecular identification by PCR and sequencing of the ...
Nagwa M. Abd El-Aziz, Bigad E. Khalil, Hayam Fouad Ibrahim   +2 more
doaj   +1 more source

How longitudinal data can contribute to our understanding of host genetic effects on the gut microbiome

Gut Microbes, 2023
A key component of microbiome research is understanding the role of host genetic influence on gut microbial composition. However, it can be difficult to link host genetics with gut microbial composition because host genetic similarity and environmental ...
Laura Grieneisen, Ran Blekhman, Elizabeth Archie   +2 more
doaj   +1 more source

Natural selection. III. Selection versus transmission and the levels of selection [PDF]

, 2011
George Williams defined an evolutionary unit as hereditary information for which the selection bias between competing units dominates the informational decay caused by imperfect transmission.
Frank, Steven A.
core   +2 more sources