Results 31 to 40 of about 293,982 (305)
Gut Microbes, 2023 A key component of microbiome research is understanding the role of host genetic influence on gut microbial composition. However, it can be difficult to link host genetics with gut microbial composition because host genetic similarity and environmental ...
Laura Grieneisen +2 more
doaj +1 more source
Expression systems for industrial Gram-positive bacteria with low guanine and cytosine content [PDF]
, 1997 Recent years have seen an increase in the development of gene expression systems for industrial Gram-positive bacteria with low guanine and cytosine content that belong to the genera Bacillus, Clostridium, Lactococcus, Lactobacillus, Staphylococcus and ...
Kleerebezem, Michiel, +2 more
core +2 more sources
Variable responses of human and non-human primate gut microbiomes to a Western diet [PDF]
, 2015 BACKGROUND: The human gut microbiota interacts closely with human diet and physiology. To better understand the mechanisms behind this relationship, gut microbiome research relies on complementing human studies with manipulations of animal models ...
Amato, Katherine R. +13 more
core +5 more sources
Evolutionary biology for the 21st century [PDF]
, 2013 New theoretical and conceptual frameworks are required for evolutionary biology to capitalize on the wealth of data now becoming available from the study of genomes, phenotypes, and organisms - including humans - in their natural environments.Molecular ...
Arnold, Stevan J. +14 more
core +5 more sources
International Journal of MicrobiologyAntimicrobial resistance remains a global concern, and there has been sustained exploration of natural products with therapeutic effects. Endophytes are among the potential microorganisms considered as the treasure chest for bioactive secondary ...
Tsedale Tasew +11 more
doaj +1 more source
mSystems, 2016 The number of samples in high-throughput comparative “omics” studies is increasing rapidly due to declining experimental costs. To keep sample data and metadata manageable and to ensure the integrity of scientific results as the scale of these projects ...
John H. Chase +3 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biotechnological Potential of Lactic Acid Bacteria Isolated From Ethiopian Honey Wine, Tej
International Journal of MicrobiologySome members of the lactic acid bacteria (LAB) have been used as probiotics. Ethiopian honey wine, Tej, may be a useful source of potential probiotic bacteria.
Minyilal Sisay +5 more
doaj +1 more source
Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli
eLife, 2017 While specific mutations allow organisms to adapt to stressful environments, most changes in an organism's DNA negatively impact fitness. The mutation rate is therefore strictly regulated and often considered a slowly-evolving parameter.
Toon Swings +8 more
doaj +1 more source