Results 21 to 30 of about 125,784 (265)
The Devil Is in the Microbial Genetic Details [PDF]
The work of Zeevi et al. (2019) in a recent issue of Nature shows that variations in gene content and organization between different strains of the same microbial species are widespread in the human gut microbiota and could be linked to many measures of health.
Adrien, Assié, Buck S, Samuel
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p63, a transcriptional factor that belongs to the p53 family, regulates epidermal differentiation, stemness, cell death, tumorigenesis, metastasis, and senescence. However, its molecular mechanism remains elusive. We report here that TAp63 phosphorylated
Norikazu Yabuta +6 more
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L-asparaginase (L-ASNase) from microbial sources is a commercially vital enzyme to treat acute lymphoblastic leukemia. However, the side effects associated with the commercial formulations of L-ASNases intrigued to explore for efficient and desired ...
Sanyukta Darnal +6 more
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CO2 and bicarbonate are required for carboxylation reactions, which are essential in most bacteria. To provide the cells with sufficient CO2, there exist two dissolved inorganic carbon supply (DICS) systems: the membrane potential-generating system ...
Sook-Ha Fan +4 more
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mSphere of Influence: Surface Sensing in Biofilm Formation
Kara B. De Leόn works in the field of microbial ecology, environmental biofilms, and microbial genetics.
Kara B. De Leόn
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New approaches to combat Porphyromonas gingivalis biofilms
In nature, bacteria predominantly reside in structured, surface-attached communities embedded in a self-produced, extracellular matrix. These so-called biofilms play an important role in the development and pathogenesis of many infections, as they are ...
Evelien Gerits +2 more
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Genetically Programmable Microbial Assembly
Engineered microbial communities show promise in a wide range of applications, including environmental remediation, microbiome engineering, and synthesis of fine chemicals. Here we present methods by which bacterial aggregates can be directed into several distinct architectures by inducible surface expression of heteroassociative protein domains ...
Mark T. Kozlowski +3 more
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Background Staphylococcus aureus spreads its infections through biofilms. This usually happens in the stationary phase of S. aureus growth where it utilizes accumulated acetate as a carbon source via the phosphotrans-acetylase-acetate kinase (Pta-Ack ...
Subbarayudu Suthi +2 more
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Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy
Bacterial biofilms rely on shared extracellular polymeric substances (EPS) and are often highly tolerant to antibiotics. Here, the authors show in in vitro experiments that Salmonella does not evolve resistance to EPS inhibition because such strains are ...
Lise Dieltjens +7 more
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A cluster of human plague cases occurred in the seaport city of Mahajanga, Madagascar, from 1991 to 1999 following 62 years with no evidence of plague, which offered insights into plague pathogen dynamics in an urban environment.
Amy J. Vogler +8 more
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