Results 191 to 200 of about 6,725,001 (330)

The divergence of mean phenotypes under persistent Gaussian selection. [PDF]

Genetics
Lynch M, Menor S.
europepmc   +1 more source

A Pangenomic Approach to Improve Population Genetics Analysis and Reference Bias in Underrepresented Middle Eastern and Horn of Africa Populations. [PDF]

Biomolecules
Oliva A, Foare R, Campbell P, Twine NA, Bauer DC, Johar AS.   +5 more
europepmc   +1 more source

Understanding the reasons for declining to participate in cancer genetics and genomic studies in the USA: a scoping review protocol. [PDF]

BMJ Open
Sanchez Mendez J, Sanchez J, Zhao C, Pankratz VS, Sussman AL, Brown-Glaberman U, Cargill S, Mishra SI, Stern MC.   +8 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Genetical Structure of Populations [PDF]

Nature, 1950
openaire   +6 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Archaic introgression and the distribution of shared variation under stabilizing selection. [PDF]

PLoS Genet
Ragsdale AP.
europepmc   +1 more source

Population Genetics in the Human Microbiome.

Trends in Genetics, 2019
Nandita R. Garud, K. Pollard
semanticscholar   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

FEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones, Laurence Seabra, Francesco Michelangeli   +2 more
wiley   +1 more source

DdRAD sequencing of the endangered species Primula Palinuri Petagna reveals high levels of inter-population diversity. [PDF]

Sci Rep
Perez-Bello P, Panero I, De Paoli E, Casolo V, Attorre F, Cambria VE, Strumia S, Santangelo A, Bonomi C, Fabrini G, Marroni F.   +10 more
europepmc   +1 more source