Results 251 to 260 of about 7,649,767 (328)

Advancements in Animal Breeding: From Mendelian Genetics to Machine Learning. [PDF]

Int J Mol Sci
Panigrahi M, Rajawat D, Nayak SS, Bose A, Bharia N, Singh S, Sharma A, Dutt T.   +7 more
europepmc   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Editorial: Genetics and justice: the implications of large-scale genome sequencing initiatives in the global south. [PDF]

Front Genet
Naslavsky MS, Jiwani T, Schwartz-Marin E.   +2 more
europepmc   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Subtype distribution, clinical presentation, and molecular spectrum of neurofibromatosis type 1-associated breast cancer. [PDF]

Breast
Di Giosaffatte N, Daniele P, Petrizzelli F, Iacovino C, Canciani C, Garau ML, Santoro C, Trevisan V, Panfili A, Cavone S, Guida V, D'Asdia MC, Bernardini L, Majore S, Ferraris A, Valiante M, Gensini F, Radio FC, Tortora G, Cassina M, Miele G, Priolo M, Sirchia F, Piccinno L, Flex E, Zampino G, Genuardi M, Nigro V, Salviati L, Papi L, Grammatico P, Leoni C, Piluso G, Giustini S, Mazza T, Upadhyaya M, Tartaglia M, Trevisson E, De Luca A.   +38 more
europepmc   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Targeted genetic screening for identifying carrier status and early-onset disease risks in Chinese newborns. [PDF]

Commun Med (Lond)
Hao C, Hu X, Guo R, Qi Z, Xie L, Jin F, Li H, Ni X, Li W.   +8 more
europepmc   +1 more source

Effect of Nonsteroidal Anti‐Inflammatory Drugs on Sacroiliac Joint Inflammation, as Seen on Magnetic Resonance Imaging, in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones, Alexander N. Bennett, Raj Sengupta, Pedro M. Machado, Helena Marzo‐Ortega, Lorna Aucott, Margaret A. Hall‐Craggs, Timothy J. P. Bray, Alan Bainbridge, Ruaridh M. Gollifer, Gary J. Macfarlane   +10 more
wiley   +1 more source

Genetic evolution of parental populations and construction of core germplasm populations in qinghai spruce seed orchard based on SLAF-seq technology. [PDF]

Front Genet
Zhao H, Xu E, Lv D, Li W, Zhao X, Jia X, Yuan H, Zhou R.   +7 more
europepmc   +1 more source

Time Trends and Predictors of Gout Remission Over 6 Years

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah, Sarah Stewart, Greg Gamble, Lisa K. Stamp, William J. Taylor, Nicola Dalbeth   +5 more
wiley   +1 more source