Results 201 to 210 of about 2,983,560 (395)

Genetics: The genetic watchmaker [PDF]

Nature, 2013
openaire   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

Cell, 2019
Cyril Neftel, J. Laffy, Mariella G. Filbin, T. Hara, M. Shore, M. Shore, G. Rahme, G. Rahme, Alyssa R. Richman, Alyssa R. Richman, Dana Silverbush, Dana Silverbush, McKenzie L. Shaw, Christine Hebert, Christine Hebert, J. DeWitt, J. DeWitt, S. Gritsch, S. Gritsch, Elizabeth M. Perez, Elizabeth M. Perez, L. Castro, Xiaoyang Lan, Xiaoyang Lan, Nicholas Druck, Christopher Rodman, Danielle Dionne, Alexander Kaplan, Mia S Bertalan, Julia L. Small, K. Pelton, Sarah Becker, D. Bonal, Q. Nguyen, Rachel L. Servis, Jeremy Fung, Ravindra Mylvaganam, L. Mayr, J. Gojo, C. Haberler, R. Geyeregger, T. Czech, I. Slavc, B. Nahed, W. Curry, B. Carter, H. Wakimoto, P. Brastianos, T. Batchelor, A. Stemmer-Rachamimov, M. Martinez-Lage, M. Frosch, I. Stamenkovic, Nicolò Riggi, Esther Rheinbay, Esther Rheinbay, Michelle Monje, O. Rozenblatt-Rosen, D. Cahill, Anoop P. Patel, T. Hunter, I. Verma, K. Ligon, K. Ligon, David N. Louis, A. Regev, A. Regev, B. Bernstein, B. Bernstein, I. Tirosh, M. Suvà, M. Suvà   +71 more
semanticscholar   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Genetics and Pathogenesis of Diffuse Large B‐Cell Lymphoma

New England Journal of Medicine, 2018
R. Schmitz, George W. Wright, D. Huang, Calvin A. Johnson, J. Phelan, James Q Wang, S. Roulland, M. Kasbekar, R. Young, A. Shaffer, D. Hodson, Wenming Xiao, Xin Yu, Yandan Yang, Hong Zhao, Weihong Xu, Xuelu Liu, Bin Zhou, Wei Du, W. Chan, E. Jaffe, R. Gascoyne, J. Connors, E. Campo, A. López-Guillermo, A. Rosenwald, G. Ott, J. Delabie, L. Rimsza, Kevin Tay Kuang Wei, A. Zelenetz, J. Leonard, N. Bartlett, Bao Tran, Jyoti Shetty, Yongmei Zhao, D. Soppet, S. Pittaluga, W. Wilson, L. Staudt   +39 more
semanticscholar   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

Molecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Expression of Concern: NKILA represses nasopharyngeal carcinoma carcinogenesis and metastasis by NF-κB pathway inhibition.

PLoS Genetics, 2022
PLOS Genetics Editors
doaj   +1 more source

The Genetics of Cancer* [PDF]

, 1933
J. B. S. Haldane
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

BioSTEM: A modern educational tool for research and innovation in the field of molecular biology and personalized medicine. [PDF]

Hum Genomics
Patrinos GP, Siamoglou S, Lazaros K, Xirafas V, Vrahatis AG, Mitropoulou C.   +5 more
europepmc   +1 more source