Results 211 to 220 of about 9,771,651 (424)

Genetics-Driven Personalized Disease Progression Model [PDF]

arXiv
Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a uniform trajectory pattern at the population level. However, chronic diseases are highly heterogeneous and often have
arxiv  

Medical genetics: advances in brief: The fish odour syndrome: biochemical, familial, and clinical aspects [PDF]

, 1994
A M Norman
openalex   +1 more source

Atopic dermatitis in diverse racial and ethnic groups—Variations in epidemiology, genetics, clinical presentation and treatment

Experimental Dermatology, 2018
B. Kaufman, E. Guttman‐Yassky, A. Alexis   +2 more
semanticscholar   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Ethical Issues in Contemporary Clinical Genetics

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2018
As genetic sequencing capabilities become more powerful and costs decline, the reach of genomics is expanding beyond research laboratories to the wards, outpatient clinics, and, with the marketing of direct-to-consumer testing services, patients’ homes ...
Genna Braverman, MD, Zachary E. Shapiro, JD, MSc, Jonathan A. Bernstein, MD, PhD   +2 more
doaj  

Next-generation sequencing for constitutional variants in the clinical laboratory, 2021 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG)

Genetics in Medicine, 2021
C. Rehder, Lora J. H. Bean, D. Bick, E. Chao, W. Chung, Soma Das, Julianne M. O’Daniel, H. Rehm, V. Shashi, L. Vincent   +9 more
semanticscholar   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

The Genetic Counseling Program at MCV [PDF]

, 1977
The Genetic Counseling Clinic at the Medical College of Virginia, established by Drs. Peter Mamunes and R.B. Young in 1973, has been supported since its inception by a clinical service grant from the National Foundation – March of Dimes; it is one of 83 ...
Mamunes, Peter, Nance, Walter E., Winter, Phyllis   +2 more
core   +1 more source

Clinical genetics of melanoma

Hereditary Cancer in Clinical Practice, 2011
Debniak T
doaj   +1 more source

Clinical genetics of familial progressive supranuclear palsy [PDF]

, 1999
Ana I. Rojo, Rosario Sánchez‐Pernaute, Aurora Fontán, Pedro Ruiz, Jérôme Honnorat, Tim Lynch, Steven S. Chin, Isabel Gonzalo, Alberto Rábano, A. Martínez, S. E. Daniel, P. Pramsteller, Huw R. Morris, Nicholas Wood, Andrew J. Lees, César Tabernero, Torbjorn Nyggard, Aileen Jackson, Anne Börjesson Hanson, Justo Garcı́a de Yébenes   +19 more
openalex   +1 more source