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Genetic Diversity on the Sex Chromosomes [PDF]
Genome Biology and Evolution, 2018 Levels and patterns of genetic diversity can provide insights into a population's history. In species with sex chromosomes, differences between genomic regions with unique inheritance patterns can be used to distinguish between different sets of possible demographic and selective events.
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Genetic Architecture and the Evolution of Sex [PDF]
Journal of Heredity, 2010 Theoretical investigations of the advantages of sex have tended to treat the genetic architecture of organisms as static and have not considered that genetic architecture might coevolve with reproductive mode. As a result, some potential advantages of sex may have been missed.
Rolf, Lohaus +2 more
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Chromosome-Wide Evolution and Sex Determination in the Three-Sexed Nematode Auanema rhodensis
G3: Genes, Genomes, Genetics, 2019 Trioecy, a mating system in which males, females and hermaphrodites co-exist, is a useful system to investigate the origin and maintenance of alternative mating strategies.
Sophie Tandonnet +6 more
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Androgens by immunoassay and mass spectrometry in children with 46,XY disorder of sex development
Endocrine Connections, 2020 Objective: Steroid measurement is a challenge in pediatric endocrinology. Currently, liquid chromatography with tandem mass spectrometry (LC-MS/MS) is considered a gold standard for this purpose. The aim of this study was to co mpare both LC-MS/MS and
Letícia Ribeiro Oliveira +10 more
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JCI Insight, 2023 Biological sex and host genetics influence HIV pathogenesis. Females have a higher likelihood of spontaneous viral control and lower set point viral load (spVL). No prior studies have assessed sex-specific genetics of HIV. To address this, we performed a
Candelaria Vergara +6 more
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Translational Psychiatry, 2021 Polygenic risk for schizophrenia has been associated with lower cognitive ability and age-related cognitive change in healthy individuals. Despite well-established neuropsychological sex differences in schizophrenia patients, genetic studies on sex ...
Elise Koch +5 more
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Gonadal sex vs genetic sex in experimental atherosclerosis
Atherosclerosis, 2023 Epidemiological data and interventional studies with hormone replacement therapy suggest that women, at least until menopause, are at decreased cardiovascular risk compared to men. Still the molecular mechanisms beyond this difference are debated and the investigation in experimental models of atherosclerosis has been pivotal to prove that the ...
Jasmine Nour +2 more
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Beyond apples and pears: sex-specific genetics of body fat percentage
Frontiers in Endocrinology, 2023 IntroductionBiological sex influences both overall adiposity and fat distribution. Further, testosterone and sex hormone binding globulin (SHBG) influence adiposity and metabolic function, with differential effects of testosterone in men and women. Here,
Delnaz Roshandel +4 more
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Sex Differences in Drosophila Somatic Gene Expression: Variation and Regulation by doublesex
G3: Genes, Genomes, Genetics, 2016 Sex differences in gene expression have been widely studied in Drosophila melanogaster. Sex differences vary across strains, but many molecular studies focus on only a single strain, or on genes that show sexually dimorphic expression in many strains ...
Michelle N. Arbeitman +5 more
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Sex‐Related Differences in Genetic Cardiomyopathies
Journal of the American Heart Association, 2022 Cardiomyopathies are a heterogeneous collection of diseases that have in common primary functional and structural abnormalities of the heart muscle, often genetically determined. The most effective categorization of cardiomyopathies is based on the presenting phenotype, with hypertrophic, dilated, arrhythmogenic, and restrictive cardiomyopathy as the ...
Alessia Argirò +8 more
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