Entomopathogenic nematodes from the genus Steinernema are lethal insect parasites that quickly kill their insect hosts with the help of their symbiotic bacteria.
Lorrayne Serra +7 more
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Revisiting Suppression of Interspecies Hybrid Male Lethality in Caenorhabditis Nematodes
Within the nematode genus Caenorhabditis, Caenorhabditis briggsae and C. nigoni are among the most closely related species known. They differ in sexual mode, with C. nigoni retaining the ancestral XO male–XX female outcrossing system, while C.
Lauren E. Ryan, Eric S. Haag
doaj +1 more source
Parallel Evolution of Two dmrt1-Derived Genes, dmy and dm-W, for Vertebrate Sex Determination
Summary: Animal sex-determining genes, which bifurcate for female and male development, are diversified even among closely related species. Most of these genes emerged independently from various sex-related genes during species diversity as ...
Yusaku Ogita +10 more
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Differential gene expression is not required for facultative sex allocation: a transcriptome analysis of brain tissue in the parasitoid wasp Nasonia vitripennis [PDF]
Whole-transcriptome technologies have been widely used in behavioural genetics to identify genes associated with the performance of a behaviour and provide clues to its mechanistic basis. Here, we consider the genetic basis of sex allocation behaviour in
Nicola Cook +7 more
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Sex, Gender, Genetics, and Health
This article addresses 2 questions. First, to what extent are sex and gender incorporated into research on genetics and health? Second, how might social science understandings of sex and gender, and gender differences in health, become more integrated into scholarship in this area?
Susan E, Short +2 more
openaire +3 more sources
Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster
Mammalian sex determination is controlled by antagonistic gene cascades operating in embryonic undifferentiated gonads. The expression of the Y-linked gene SRY is sufficient to trigger the testicular pathway, whereas its absence in XX embryos leads to ...
Alicia Hurtado +8 more
doaj +1 more source
Performance of mutation pathogenicity prediction tools on missense variants associated with 46,XY differences of sex development [PDF]
OBJECTIVES: Single nucleotide variants (SNVs) are the most common type of genetic variation among humans. High-throughput sequencing methods have recently characterized millions of SNVs in several thousand individuals from various populations, most of ...
Luciana R. Montenegro +4 more
doaj +2 more sources
Unveiling the Significance of the Androgen Receptor Gene in Disorders of Sex Development
Disorders of sex development (DSD) encompass a range of congenital conditions where the development of chromosomal, gonadal or anatomical sex is atypical. There are many genes associated with DSD, and one of them is the androgen receptor (AR) gene, which
Ziske Maritska +5 more
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Genetics of hypertension-related sex differences and hypertensive disorders of pregnancy
Background: Hypertension and hypertensive disorders of pregnancy (HDP) cause a significant burden of disease on societies and individuals by increasing cardiovascular disease risk.
Jouko Nurkkala +3 more
doaj +1 more source
Animals’ response to acute stress is known to be influenced by sex and genetics. Here the authors performed RNA-seq on actively translated mRNAs in hippocampal CA3 neurons in mice, and document the effects of sex and genotype (i.e., BDNF Val66Met) on ...
Jordan Marrocco +8 more
doaj +1 more source

