Results 41 to 50 of about 272,074 (162)

Hybrid Assembly of the Genome of the Entomopathogenic Nematode Steinernema carpocapsae Identifies the X-Chromosome

open access: yesG3: Genes, Genomes, Genetics, 2019
Entomopathogenic nematodes from the genus Steinernema are lethal insect parasites that quickly kill their insect hosts with the help of their symbiotic bacteria.
Lorrayne Serra   +7 more
doaj   +1 more source

Revisiting Suppression of Interspecies Hybrid Male Lethality in Caenorhabditis Nematodes

open access: yesG3: Genes, Genomes, Genetics, 2017
Within the nematode genus Caenorhabditis, Caenorhabditis briggsae and C. nigoni are among the most closely related species known. They differ in sexual mode, with C. nigoni retaining the ancestral XO male–XX female outcrossing system, while C.
Lauren E. Ryan, Eric S. Haag
doaj   +1 more source

Parallel Evolution of Two dmrt1-Derived Genes, dmy and dm-W, for Vertebrate Sex Determination

open access: yesiScience, 2020
Summary: Animal sex-determining genes, which bifurcate for female and male development, are diversified even among closely related species. Most of these genes emerged independently from various sex-related genes during species diversity as ...
Yusaku Ogita   +10 more
doaj   +1 more source

Differential gene expression is not required for facultative sex allocation: a transcriptome analysis of brain tissue in the parasitoid wasp Nasonia vitripennis [PDF]

open access: yesRoyal Society Open Science, 2018
Whole-transcriptome technologies have been widely used in behavioural genetics to identify genes associated with the performance of a behaviour and provide clues to its mechanistic basis. Here, we consider the genetic basis of sex allocation behaviour in
Nicola Cook   +7 more
doaj   +1 more source

Sex, Gender, Genetics, and Health

open access: yesAmerican Journal of Public Health, 2013
This article addresses 2 questions. First, to what extent are sex and gender incorporated into research on genetics and health? Second, how might social science understandings of sex and gender, and gender differences in health, become more integrated into scholarship in this area?
Susan E, Short   +2 more
openaire   +3 more sources

Complete male-to-female sex reversal in XY mice lacking the miR-17~92 cluster

open access: yesNature Communications
Mammalian sex determination is controlled by antagonistic gene cascades operating in embryonic undifferentiated gonads. The expression of the Y-linked gene SRY is sufficient to trigger the testicular pathway, whereas its absence in XX embryos leads to ...
Alicia Hurtado   +8 more
doaj   +1 more source

Performance of mutation pathogenicity prediction tools on missense variants associated with 46,XY differences of sex development [PDF]

open access: yesClinics
OBJECTIVES: Single nucleotide variants (SNVs) are the most common type of genetic variation among humans. High-throughput sequencing methods have recently characterized millions of SNVs in several thousand individuals from various populations, most of ...
Luciana R. Montenegro   +4 more
doaj   +2 more sources

Unveiling the Significance of the Androgen Receptor Gene in Disorders of Sex Development

open access: yesAdvances in Human Biology
Disorders of sex development (DSD) encompass a range of congenital conditions where the development of chromosomal, gonadal or anatomical sex is atypical. There are many genes associated with DSD, and one of them is the androgen receptor (AR) gene, which
Ziske Maritska   +5 more
doaj   +1 more source

Genetics of hypertension-related sex differences and hypertensive disorders of pregnancy

open access: yesBlood Pressure
Background: Hypertension and hypertensive disorders of pregnancy (HDP) cause a significant burden of disease on societies and individuals by increasing cardiovascular disease risk.
Jouko Nurkkala   +3 more
doaj   +1 more source

A sexually dimorphic pre-stressed translational signature in CA3 pyramidal neurons of BDNF Val66Met mice

open access: yesNature Communications, 2017
Animals’ response to acute stress is known to be influenced by sex and genetics. Here the authors performed RNA-seq on actively translated mRNAs in hippocampal CA3 neurons in mice, and document the effects of sex and genotype (i.e., BDNF Val66Met) on ...
Jordan Marrocco   +8 more
doaj   +1 more source

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