Results 11 to 20 of about 16,868 (148)

Oral fexinidazole for stage 1 or early stage 2 African Trypanosoma brucei gambiense trypanosomiasis: a prospective, multicentre, open-label, cohort study

The Lancet Global Health, 2021
Summary: Background: Staging and treatment of human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT) required lumbar puncture to assess cerebrospinal fluid (CSF) and intravenous drugs that cross the blood–brain barrier for late ...
Victor Kande Betu Ku Mesu, DPH, Wilfried Mutombo Kalonji, MD, Clélia Bardonneau, MSc, Olaf Valverde Mordt, MSc, Digas Ngolo Tete, MPH, Séverine Blesson, MSc, François Simon, MSc, Sophie Delhomme, MSc, Sonja Bernhard, PhD, Hélène Mahenzi Mbembo, MD, Christian Mpia Moke, MD, Steven Lumeya Vuvu, MMed, Junior Mudji E'kitiak, MD, Felix Akwaso Masa, MD, Melchias Mukendi Ilunga, MD, Dieudonné Mpoyi Muamba Nzambi, MD, Tim Mayala Malu, MD, Serge Kapongo Tshilumbwa, MD, Franck Botalema Bolengi, MD, Mathieu Nkieri Matsho, MD, Crispin Lumbala, MPH, Bruno Scherrer, PhD, Nathalie Strub-Wourgaft, MD, Antoine Tarral, MD   +23 more
doaj   +1 more source

A four-step process for building sustainable access to diagnosis and treatment of Chagas disease

Revista Panamericana de Salud Pública, 2019
The vast majority of people with Chagas disease (CD) are undiagnosed and untreated. Improving access to diagnosis and treatment for CD involves confronting a wide range of barriers. This report discusses a collaborative approach to eliminate barriers and
Carolina Batista, Colin J. Forsyth, Rafael Herazo, Marina Pereira Certo, Andrea Marchiol   +4 more
doaj   +1 more source

Epilepsy in the Sanaga‐Mbam valley, an onchocerciasis‐endemic region in Cameroon: electroclinical and neuropsychological findings

Epilepsia Open, 2021
Objective Epilepsy is highly prevalent in onchocerciasis‐endemic African regions. Various types of epilepsy have been described in such regions based essentially on clinical characteristics.
Alexandre Morin, Maxime Guillaume, Leonard Ngarka, Godwin Y. Tatah, Joseph Nelson Siewe Fodjo, Guillaume Wyart, Ghislain Nokam, Thierry Tchoumi, Mary Bello Nkinin, Wepnyu Y. Njamnshi, Eric‐Samuel Chokote, Michel Boussinesq, Robert Colebunders, Cédric B. Chesnais, Gilles Gargala, Dominique Parain, Alfred K. Njamnshi   +16 more
doaj   +1 more source

Assessing the impact of simplified HCV care on linkage to care amongst high-risk patients at primary healthcare clinics in Malaysia: a prospective observational study

BMJ Open, 2021
Introduction To achieve the elimination of hepatitis C virus (HCV), substantial scale-up in access to testing and treatment is needed. This will require innovation and simplification of the care pathway, through decentralisation of testing and treatment ...
Jagpreet Chhatwal, Shahnaz Murad, Suresh Kumar, Fatanah Ismail, Philippa Easterbrook, Rozainanee Mohd Zain, Jessica Markby, Sonjelle Shilton, Xiaohui Sem, Huan Keat Chan, Rosaida Md Said, Sasikala Siva, Zalwani Zainuddin, Norasiah Abu Bakar, Haniza Omar, Ryan Jose III Ruiz, Mary Gaeddert, Alexander Tyshkovskiy, Madeline Adee, Jean-Michel Piedagnel, Caroline Menétrey, Fazidah Yuswan, Nazrila Hairizan Nasir, Isabelle Andrieux-Meyer, Rozita Zakaria, Ruziaton Hasim, Muhammad Radzi Abu Hassan   +26 more
doaj   +1 more source

Open Source Hardware, Exploring how Industry Regulation Affects Knowledge Commons Governance: An Exploratory Case Study

International Journal of the Commons, 2021
Tools for clinical examination have not fundamentally evolved since the invention of the stethoscope by René Laennec in the nineteenth century. However, three decades ago, the medical community started to consider repurposing ultrasound scanners to ...
Pascal Carpentier
doaj   +1 more source

The drug and vaccine landscape for neglected diseases (2000–11): a systematic assessment

The Lancet Global Health, 2013
Background: In 1975–99, only 1·1% of new therapeutic products had been developed for neglected diseases. Since then, several public and private initiatives have attempted to mitigate this imbalance.
Dr. Belen Pedrique, MD, Nathalie Strub-Wourgaft, MD, Claudette Some, PharmD, Piero Olliaro, MD, Patrice Trouiller, PharmD, Nathan Ford, PhD, Bernard Pécoul, MD, Jean-Hervé Bradol, MD   +7 more
doaj   +1 more source

Introduction to the Special Issue on Indigenous and Afrodescendant Movements and Organizations in Latin America: Negotiating, Resisting, Performing and Re-purposing Dominant Categories

Alternautas, 2022
In 2018 the Albert Hirschman Centre on Democracy in Geneva organized together with Europaeum and Alternautas, the workshop on “Democracy, Indigenous Rights and Ethno-Racial Mobilization: Latin America in Comparative Perspective.” This workshop was part ...
Diego Silva, Nancy Postero
doaj   +1 more source

Target Product Profile for a point-of-care diagnostic test for dermal leishmaniases

Parasite Epidemiology and Control, 2019
Objectives: Localized cutaneous leishmaniasis and its evolving forms diffuse cutaneous leishmaniasis, mucosal leishmaniasis and cutaneous leishmaniasis recidivans, together with the visceral leishmaniasis sequelae post-kala azar dermal leishmaniasis ...
Israel Cruz, Audrey Albertini, Mady Barbeitas, Byron Arana, Albert Picado, Jose A. Ruiz-Postigo, Joseph M. Ndung'u   +6 more
doaj   +1 more source

Estimating the reproduction number from the initial phase of the Spanish flu pandemic waves in Geneva, Switzerland

Mathematical Biosciences and Engineering, 2007
At the outset of an influenza pandemic, early estimates of the number of secondary cases generated by a primary influenza case (reproduction number, R) and its associated uncertainty can help determine the intensity of interventions necessary for control.
Gerardo Chowell, Catherine E. Ammon, Nicolas W. Hengartner, James M. Hyman   +3 more
openaire   +3 more sources

Challenges of sharing individual participant data for secondary research on neglected tropical diseases: the experience of Drugs for Neglected Diseases initiative and a call for action

BMJ Open
Introduction The Drugs for Neglected Diseases initiative (DNDi) is committed to maximising the scientific value of the individual participant data (IPD) it has collected during its 20 years of activity and the IPD it will collect in the future, while ...
Anastassia Negrouk, Thaddaeus Egondi, Craig Tipple, Justyna Tarwid, Michelle Childs, Dominique Junod-Moser   +5 more
doaj   +1 more source