Results 21 to 30 of about 263,810 (291)

Estimating the reproduction number from the initial phase of the Spanish flu pandemic waves in Geneva, Switzerland

open access: yesMathematical Biosciences and Engineering, 2007
At the outset of an influenza pandemic, early estimates of the number of secondary cases generated by a primary influenza case (reproduction number, R) and its associated uncertainty can help determine the intensity of interventions necessary for control.
Gerardo Chowell   +3 more
openaire   +3 more sources

The Development of an Information Society and Electronic Commerce in the European Union in the Context of Selected Documents of the EU and International Organisations [PDF]

open access: yes, 2012
In this article, the author presents selected documents on electronic commerce published by the United Nations Commission on International Trade Law, the World Trade Organization, the Organisation for Economic Cooperation and Development, the ...
M. Feltynowski, T. Czajkowski
core   +1 more source

Challenges of sharing individual participant data for secondary research on neglected tropical diseases: the experience of Drugs for Neglected Diseases initiative and a call for action

open access: yesBMJ Open
Introduction The Drugs for Neglected Diseases initiative (DNDi) is committed to maximising the scientific value of the individual participant data (IPD) it has collected during its 20 years of activity and the IPD it will collect in the future, while ...
Anastassia Negrouk   +5 more
doaj   +1 more source

Target Product Profile for a point-of-care diagnostic test for dermal leishmaniases

open access: yesParasite Epidemiology and Control, 2019
Objectives: Localized cutaneous leishmaniasis and its evolving forms diffuse cutaneous leishmaniasis, mucosal leishmaniasis and cutaneous leishmaniasis recidivans, together with the visceral leishmaniasis sequelae post-kala azar dermal leishmaniasis ...
Israel Cruz   +6 more
doaj   +1 more source

International law-making and the Geneva Declaration on Human Rights at Sea

open access: yesLeiden Journal of International Law
The Geneva Declaration on Human Rights at Sea is a recent initiative of the non-governmental organization (NGO), Human Rights at Sea, and provides an opportunity to examine how an NGO-led initiative may contribute to international law-making.
Natalie Klein
doaj   +1 more source

Completion of the Common Internal Market of Recycling in the EU - Position of New Member States [PDF]

open access: yes, 2010
In the paper will be presented the analysis of ecological competitiveness in the EU ("old" and "new" Member States) recycling market within the process of the establishment of common standards related to the Prevention and Recycling of Waste.
Wysokińska Zofia
core   +2 more sources

Model‐Informed Drug Development of a Sustained Release Formulation of Flucytosine in the Treatment of Cryptococcal Meningitis: A Case Study Using Physiologically Based Pharmacokinetic Modeling

open access: yesCPT: Pharmacometrics & Systems Pharmacology
This paper presents a case study demonstrating the application of model‐informed drug development (MIDD) and early modeling integration in the development of a sustained release (SR) formulation of flucytosine for cryptococcal meningoencephalitis (CM) in
Johanna Eriksson   +8 more
doaj   +1 more source

WHO Framework Convention on Tobacco Control [PDF]

open access: yes, 2012
Annotated and edited transcript of a Witness Seminar in collaboration with the Department of Kowledge Management and Sharing, WHO, held in Geneva, 26 February 2010.
REYNOLDS, LA, TANSEY, EM
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Giving regenerative agriculture an agronomic perspective: a proposed framework from the food and beverage industry

open access: yesFrontiers in Sustainable Food Systems
Food systems face significant challenges that include increasing demand for agricultural products and accelerating environmental degradation. Regenerative agriculture has emerged as concept to reduce environmental harm while maintaining or even improving
Dominik Klauser   +13 more
doaj   +1 more source

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