Results 171 to 180 of about 2,047,215 (274)

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

Molecular profiling and phenotypic evaluation of thermo-sensitive genic male sterility genes for high-yielding rice hybrids (<i>Oryza sativa</i> L.). [PDF]

PeerJ
Naidu BN, Swaminathan M, Rakkimuthu N, Ramamoorthy P, Dharmalingam K, Muthurajan R, Duraisamy S, Mohanty TA, John BA.   +8 more
europepmc   +1 more source

MOLECULAR MECHANISM OF MALE STERILITY IN PLANTS

Male sterility, defined as the absence or non-functionality of viable pollen grains, is a widespread and agriculturally important phenomenon in flowering plants.
Dr. R. B. Madariya, Sneha Vaibhav Chauhan, Harsh Harilal Maru   +2 more
core   +1 more source

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

Advanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou, Jiwei Sun, Peng Chen, Caihong Mao, Junyuan Zhang, Haoqi Lei, Xiaoqing Han, Yaxuan Zhang, Yuheng Jiang, Yulin Jia, Bin Su, Lili Chen   +11 more
wiley   +1 more source

Impaired 2',3'-cyclic phosphate tRNA repair causes thermo-sensitive genic male sterility in rice. [PDF]

Cell Res
Yan B, Liu C, Sun J, Mao Y, Zhou C, Li J, Liu W, Li S, Yan W, Fu C, Qin P, Fu X, Zhao X, Song X, Nie J, Gao F, Yang Y, Chen Y, Cao X.   +18 more
europepmc   +1 more source

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Gene characterization and molecular pathway analysis of reverse thermosensitive genic male sterility in eggplant (Solanum melongena L.). [PDF]

Hortic Res, 2019
Li B, Chen X, Wu Y, Gu A, Zhang J, Luo S, Gao X, Zhao J, Pan X, Shen S.   +9 more
europepmc   +1 more source

Genome-wide identification of CaWD40 proteins reveals the involvement of a novel complex (CaAN1-CaDYT1-CaWD40-91) in anthocyanin biosynthesis and genic male sterility in Capsicum annuum. [PDF]

BMC Genomics
Tang P, Huang J, Wang J, Wang M, Huang Q, Pan L, Liu F.   +6 more
europepmc   +1 more source

Transcriptomic analysis reveals the mechanism of thermosensitive genic male sterility (TGMS) of Brassica napus under the high temperature inducement. [PDF]

BMC Genomics, 2019
Tang X, Hao YJ, Lu JX, Lu G, Zhang T.
europepmc   +1 more source