Results 91 to 100 of about 31,152 (194)
The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha +4 more
wiley +1 more source
Plant‐Derived Polyphenols for Sustainable Flame‐Retardant Coatings
This review compares plant‐derived polyphenolic flame retardants by synthesizing literature on their mechanisms, synergistic effects, and performance across polymers, wood, fibers, and coatings, while examining biodegradability, life cycle assessment, safe‐and‐sustainable‐by‐design, and consistency with circular‐economy principles for sustainable fire ...
Myeongjun Song, Woo Rin Lee, Kyueui Lee
wiley +1 more source
Anti‐TPO levels, along with waist circumference and waist‐to‐hip ratio, showed notable reductions in the curcumin group compared to placebo, while other thyroid‐related and metabolic markers remained largely unchanged. ABSTRACT Background Hashimoto's thyroiditis (HT) is an inflammatory autoimmune disease and patients with HT may benefit from ...
Fatemeh Bourbour +6 more
wiley +1 more source
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli +8 more
wiley +1 more source
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
ABSTRACT Dietary fiber is a bioactive substance that can modulate gut microbiota and exert a relieving effect on inflammatory bowel disease (IBD). Dendrobium officinale polysaccharide (DOP) is a type of bioactive dietary fiber that has been proven to have various biological activities on intestinal function.
Jie Xu +7 more
wiley +1 more source
Biological activities, health benefits and structures of equol and its derivatives. ABSTRACT Equol is a metabolite transformed from daidzein by intestinal microorganisms and has received extensive attention due to its various pharmacological activities and therapeutic potential.
Jiao‐Jiao Zhuo +2 more
wiley +1 more source
Molecular docking analysis reveals the functional inhibitory effect of Genistein and Quercetin on TMPRSS2: SARS-COV-2 cell entry facilitator spike protein [PDF]
Reji Manjunathan +8 more
openalex +1 more source
Wnt Signaling Pathway: Biological Function, Diseases, and Therapeutic Interventions
The Wnt signaling pathway is essential for development and tissue homeostasis, while its dysregulation drives diverse diseases. This review systematically outlines its components, functions, regulators, and preclinical models, highlighting secreted frizzled‐related proteins (SFRPs) as context‐dependent, biphasic modulators.
Xiaoyu Jin +3 more
wiley +1 more source

