Results 101 to 110 of about 61,268 (292)

Genistein Inhibits Rat Aortic Smooth Muscle Cell Proliferation Through the Induction of p27kip1

open access: yesJournal of Pharmacological Sciences, 2008
Diet is one of the most important factors that influence the risks for cardiovascular diseases. Genistein, an isoflavone found in soy, may benefit the cardiovascular system. Here, we investigated the effect of genistein on platelet-derived growth factor (
Ji-Yeon Yu   +6 more
doaj   +1 more source

Protective effect of genistein on radiation-induced intestinal injury in tumor bearing mice [PDF]

open access: yes, 2013
BACKGROUND: Radiation therapy is the most widely used treatment for cancer, but it causes the side effect of mucositis due to intestinal damage.
Changjong Moon   +7 more
core   +1 more source

Metabolomic Differentiation of Malpighiaceae From Dry and Humid Tropics via UHPLC‐MS/MS and Chemometrics

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Various factors can trigger water stress in plants, particularly in those growing in dry tropical regions. To survive under such conditions, plants produce metabolites with adaptive functions. However, metabolomic data on the leaves of Malpighiaceae species cultivated in both dry and humid tropical areas of Brazil remain scarce.
Jaqueline Munise Guimarães da Silva   +2 more
wiley   +1 more source

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis [PDF]

open access: yes, 2014
Dietary consumption of genistein, found in soy, has been associated with a potentially protective role in colorectal cancer (CRC) development and progression.
Bergan, Raymond C   +9 more
core   +3 more sources

Advances in Eco‐Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
Fruit bioactive compounds offer antioxidant, anti‐inflammatory, and preventive benefits, yet extraction is hindered by poor solubility and conventional methods using toxic solvents and high energy. This review evaluates traditional and advanced eco‐friendly technologies, highlighting efficiency, selectivity, and sustainability.
Abadi Gebreyesus Hndeya   +2 more
wiley   +1 more source

Genistein induces a protective immunomodulatory effect in a mouse model of cervical cancer [PDF]

open access: yes, 2012
Background: Genistein (GEN), a naturally occurring flavonoid present in soy bean, has attracted scientific interest for its possible benefits in cancer. Objective: The potential immunomodulatory effects of genistein on the immune system and against TC-1 ...
Alizadeh, A.   +7 more
core   +1 more source

A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials [PDF]

open access: yes, 2017
There is no treatment for the myelin loss in multiple sclerosis, ultimately resulting in the axonal degeneration that leads to the progressive phase of the disease.
Agresti, C.   +11 more
core   +2 more sources

Equol Alleviates Postmenopausal Metabolic Dysfunction‐Associated Steatotic Liver Disease via the GPR30/PI3K Pathway

open access: yeseFood, Volume 7, Issue 3, June 2026.
This study demonstrates that equol exerts a protective effect on metabolic dysfunction‐associated steatotic liver disease in both in vivo and in vitro by activating the GPR30/PI3K/Nrf2 signaling pathway. Equol's interaction with GPR30 and its ability to activate the PI3K/Nrf2 pathway provide a promising therapeutic strategy for treating metabolic ...
Hanqiang Cui   +8 more
wiley   +1 more source

Effect of Genistein on Starch Digestion In Vitro and Its Mechanism of Action

open access: yesFoods
The digestive properties of starch are crucial in determining postprandial glycaemic excursions. Genistein, an active phytoestrogen, has the potential to influence starch digestion rates.
Jianhui Jia   +5 more
doaj   +1 more source

Dietary intake of genistein suppresses hepatocellular carcinoma through AMPK-mediated apoptosis and anti-inflammation

open access: yesBMC Cancer, 2019
Background Women have a lower risk of hepatocellular carcinoma (HCC) than men, and the decreased possibility of HCC in women is thought to depend on estrogen levels.
Sang R. Lee   +11 more
doaj   +1 more source

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