Results 121 to 130 of about 61,268 (292)
Regioselective sonochemical synthesis of genistein derivatives
Differential functionalization of the phenolic groups in genistein was carried out in excellent yields under ultrasonic irradiation. The isoflavone ring had proved to be unstable under stirring at 60 degrees C and phenyl benzyl ketone was unexpectedly isolated instead of the genistein derivative.
S F, Wang, Y H, Ye, Z, Zhang, R X, Tan
openaire +2 more sources
African walnut oil and docosahexaenoic acid administration to female Wistar rats with DMBA‐induced breast cancer may delay tumor growth, increase white blood cells, platelets and mean corpuscular hemoglobin counts in the blood. DMBA significantly lowers red blood cells, hemoglobin levels, and protein concentration.
Fabrice Tonfack Djikeng +3 more
wiley +1 more source
Effect of carbaryl on some biochemical changes in PC12 cells: the protective effect of soy isoflavone genistein, and daidzein, and their mixed solution [PDF]
Meng−Lei Xu +8 more
openalex +1 more source
This study employs an interpretable machine learning framework to predict diabetes‐cancer comorbidity, with the Random Forest and LightGBM models demonstrating exceptional performance. SHAP value analysis reveals that while advanced age and cardiometabolic dysfunctions serve as primary risk drivers, dietary antioxidants (particularly daidzein and ...
Ming Xu +8 more
wiley +1 more source
Inhibitory Effect of Genistein on α-Glucosidase and Its Molecular Mechanism
To investigate the inhibitory effects of genistein on α-glucosidase activity, the effects of genistein on starch digestion characteristics were determined by in vitro digestion assays. The type and molecular mechanism of inhibition were examined based on
Jianhui JIA +5 more
doaj +1 more source
Improvement of genistein content in solid genistein/-cyclodextrin complexes β
Genistein:β-cyclodextrin complexes with high drug loading (19.22%) were prepared by freeze-drying and characterized by differential scanning calorimetry and hydrogen nuclear magnetic resonance spectroscopy. The spatial configuration of the complex was proposed by means of 2D-NOESY experiment combined with molecular modeling.
Clarissa R. Xavier +9 more
openaire +1 more source
This illustration highlights how dietary polyphenols from foods like berries, grapes, and green tea travel through the gut, where microbiota transform them into bioactive metabolites. These metabolites pass into the bloodstream, strengthen the gut barrier, and ultimately reach the brain, supporting neuroprotection through antioxidative and anti ...
Adnan Akif +3 more
wiley +1 more source
Design and Characterization of a Transethosome-Based Gel for Cutaneous Administration of Genistein
In this study, lipid nanovesicular systems such as ethosome and transethosome dispersions were studied as potential vehicles for the cutaneous administration of genistein, an isoflavone with antioxidant and chemopreventive properties.
Federico Santamaria +13 more
doaj +1 more source
ABSTRACT Cancer cachexia (CC) is a complex pathological condition associated with cancer progression and poor prognosis, particularly in gastrointestinal cancers, and is closely linked to the gut microbiota. Lipolysis in CC may play a key role in driving cachexia progression.
Jiaqi Wang +11 more
wiley +1 more source

