Results 251 to 260 of about 61,268 (292)

Reactions of Genistein with Alkylperoxyl Radicals

Chemical Research in Toxicology, 2000
Antioxidant actions of the soy isoflavone genistein are believed to contribute to its overall chemopreventive activity. However, the mechanisms of its antioxidant reactions remain unknown. The objective of this study was to characterize the reaction products of genistein (5,7,4'-trihydroxyisoflavone) with peroxyl radicals generated by thermolysis of 2 ...
A, Arora, S, Valcic, S, Cornejo, M G, Nair, B N, Timmermann, D C, Liebler   +5 more
openaire   +2 more sources

Direct action of genistein on CFTR

Pfl�gers Archiv European Journal of Physiology, 1997
Human cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels were expressed in oocytes from Xenopus laevis after injection of CFTR cRNA and studied with the two-electrode voltage-clamp and the giant patch techniques. The tyrosine kinase inhibitor genistein alone activated a small chloride current in whole oocytes expressing CFTR ...
Weinreich, F., Wood, P., Riordan, J., Nagel, G.   +3 more
openaire   +3 more sources

Synthesis of Selectively Protected Genistein Derivatives

Synthetic Communications, 2003
Differential functionalization of the phenolic groups in Genistein by sequential silylation/acylation reactions, involving some unexpected regioselective O-silyl group replacement, is described.
Wieslaw Szeja, Gabriela Pastuch, Ilona Wandzik, Nikodem Kuznik, Grzegorz Grynkiewicz   +4 more
openaire   +1 more source

Genistein as an anti-inflammatory agent

Inflammation Research, 2003
The aim of this study was to investigate the impact of the isoflavone genistein on in vivo cell-mediated responses. In addition, we wanted to study the influence of genistein on collagen induced arthritis (CIA) in mice.Delayed type hypersensitivity reaction (DTH) to oxazolone and the inflammatory response to olive oil were measured in mice treated with
M, Verdrengh, I M, Jonsson, R, Holmdahl, A, Tarkowski   +3 more
openaire   +2 more sources

Chemoprevention by Genistein

2017
Genistein (4,5,7-trihydroxyisoflavone) is a typical example of a phytoestrogenic compound, polyphenolic isoflavone, found in soy products, obtained primarily from Genista tinctoria L. in 1899 and named after the genus of this plant. Genistein is synthesized through transfer of (2S)-naringin into genistein by NAD(P)H in aerobic conditions and in the ...
openaire   +1 more source

EFFECTS OF ORAL GENISTEIN IN MICE

Pediatric Pathology & Molecular Medicine, 2003
In cell culture systems, genistein, a soy-derived isoflavone with chemopreventive and estrogenic effects, enhances cAMP-dependent activation of the most common cystic fibrosis-causing mutation, deltaF508-CFTR, by as much as 20-fold. DeltaF508-CFTR is present in the apical membrane at far lower levels than wild-type CFTR. If genistein can enhance cyclic
Anita, Bhandari, Susan E, Crawford, Lijun, Huang, William W, Reenstra   +3 more
openaire   +2 more sources

Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

Cell, 2022
Tzu-Tang Wei, Mark Chandy, Masataka Nishiga   +2 more
exaly  

Genistein and daidzein

2022
Loveleen Sarao, Sandeep Kaur, Tanu Malik, Ajay Singh   +3 more
openaire   +1 more source

genistein, n.

2023
openaire   +1 more source

Dietary genistein increases microbiota-derived short chain fatty acid levels, modulates homeostasis of the aging gut, and extends healthspan and lifespan

Pharmacological Research, 2023
Bingkun Zhang, Chaoyong Liao, Jiaqi Lei
exaly