Results 241 to 250 of about 61,268 (292)
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Phytochemistry, 2002
Genistein (4',5,7-trihydroxyisoflavone) is a common precursor in the biosynthesis of antimicrobial phytoalexins and phytoanticipins in legumes, and an important nutraceutical molecule found in soybean seeds. Genistein is a phytoestrogen with a wide variety of pharmacological effects in animal cells, including tyrosine kinase inhibition, and dietary ...
Richard A, Dixon, Daneel, Ferreira
exaly +3 more sources
Genistein (4',5,7-trihydroxyisoflavone) is a common precursor in the biosynthesis of antimicrobial phytoalexins and phytoanticipins in legumes, and an important nutraceutical molecule found in soybean seeds. Genistein is a phytoestrogen with a wide variety of pharmacological effects in animal cells, including tyrosine kinase inhibition, and dietary ...
Richard A, Dixon, Daneel, Ferreira
exaly +3 more sources
Genistein and hematological malignancies
Cancer Letters, 2010Genistein is an isoflavanoid from soybeans and promising cancer chemotherapeutic agent. Genistein exposure varies widely because of cultural differences in diet. Hypothetically, this could account for differential cancer risk across ethnic populations.
Wang, Li +3 more
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Genistein attenuates choroidal neovascularization
The Journal of Nutritional Biochemistry, 2014Genistein is a dietary-derived flavonoid abundantly present in soybeans and known to possess various biological effects including anti-inflammation and anti-angiogenic activity. To investigate the effects of genistein on intraocular neovascularization, we used an animal model of laser-induced choroidal neovascularization (CNV).
Satoshi, Kinoshita +9 more
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Genetic toxicity studies with genistein
Food and Chemical Toxicology, 2006Genistein is a phytoestrogen that occurs naturally in the diet especially in soybeans and soy-based foods. Genistein and related phytoestrogens are of interest as chemopreventive agents for a variety of diseases and cancers based on epidemiologic evidence of reduced cancer rates in populations with a high intake of soy.
R, Michael McClain +3 more
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Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2005
Soy-derived isoflavone phytoestrogens, such as genistein (4',5,7-trihydroxyisoflavone), have been shown to protect low-density lipoprotein from oxidation. In addition, human plasma was previously shown to be capable of converting genistein into lipophilic fatty acid esters that accumulate in lipoproteins in vitro.
Maija, Badeau +7 more
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Soy-derived isoflavone phytoestrogens, such as genistein (4',5,7-trihydroxyisoflavone), have been shown to protect low-density lipoprotein from oxidation. In addition, human plasma was previously shown to be capable of converting genistein into lipophilic fatty acid esters that accumulate in lipoproteins in vitro.
Maija, Badeau +7 more
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Radical scavenging properties of genistein
Free Radical Biology and Medicine, 2003The reactivity of genistein toward reactive radical species has been investigated by means of pulse radiolysis. The values of rate constants, respectively 2.3 x 10(10) M(-1)s(-1) and 1.3 x 10(10) M(-1)s(-1) for the reaction with hydroxyl radical at pH 8.3 and 3.0, are close to diffusion limit indicating that genistein is a potent hydroxyl radical ...
Jacek, Zielonka +2 more
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Cardiovascular Effects of the Phytoestrogen Genistein
Current Medicinal Chemistry-Cardiovascular & Hematological Agents, 2004Phytoestrogenic molecules have received a great deal of attention over the last few years because of their potentially preventive roles against a few of today's most prevalent chronic diseases, namely cardiovascular diseases, osteoporosis and hormone related cancers.
ALTAVILLA, Domenica +7 more
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Genistein suppresses mammary cancer in rats
Carcinogenesis, 1995Female Sprague-Dawley CD rats were injected s.c. with 5 mg genistein, a soy phytoestrogen, or 20 microliters of the vehicle, dimethylsulfoxide (DMSO), on days 2,4 and 6 postpartum. At day 50, they were exposed to 80 micrograms dimethylbenz[a]anthracene (DMBA)/g body wt. Animals treated neonatally with genistein as compared to DMSO had increased latency
C A, Lamartiniere +5 more
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