Results 181 to 190 of about 187,934 (264)

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Retrospective evaluation of palliative care consultation in critically ill adult and pediatric cancer subjects

Pediatric Investigation, EarlyView.
Children with cancer received more palliative care consultation before, but fewer during, critical illness compared with adults. This disparity suggests underuse of palliative care during pediatric critical care. ABSTRACT Importance Palliative care consultation is an essential component of comprehensive care for patients with cancer during critical ...
Conrad Krawiec, Neal Thomas
wiley   +1 more source

Hypovitaminosis D in acute inpatient cancer rehabilitation: Prevalence, predictors, and practical implications

PM&R, EarlyView.
Abstract Background Hypovitaminosis D is associated with adverse health outcomes, including increased mortality in patients with cancer. Although vitamin D insufficiency (23%–72%) and deficiency (20%–71%) are common among patients admitted to inpatient rehabilitation, their prevalence and predictors in cancer‐specific inpatient rehabilitation ...
Jegy M. Tennison, Minxing Chen, Areeba Hafeez, Ananya Krishnan, Sefia Khan, Rony Dev, Sonal Admane, Eduardo Bruera   +7 more
wiley   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Dose‐dependent efficacy of a novel dsRNA‐based solution containing vadescana for Varroa destructor control

Pest Management Science, EarlyView.
Vadescana is a novel dsRNA‐based product that targets Varroa fecundity. Vadescana applied at 4 g/brood box in one application was most effective at reducing Varroa populations for up to 18 weeks. Abstract BACKGROUND A novel dsRNA‐based product, containing a molecule called vadescana, interferes with Varroa destructor (Anderson and Trueman) fecundity ...
Briana E Price, Ryan Kuesel, Taylor Reams, Brian Manley, James Masucci, Brandon K Hopkins   +5 more
wiley   +1 more source

Understanding Interactions Between Sustainable Development Goals Within and Between Policy Programmes: The Case of Kenya's Dairy Sector

Sustainable Development, EarlyView.
ABSTRACT Achieving Agenda 2030 depends on addressing interactions between the sustainable development goals (SDGs). In this paper, we conceptualize SDG interactions as synergies or trade‐offs, incoming or outgoing, and internal or external, and analyze how SDG 2 (Zero Hunger) interacts with other SDGs within and across policy programmes that support ...
Annita Jepchirchir Kirwa, Sylvia Karlsson‐Vinkhuyzen, Todd Andrew Crane, Art R. P. J. Dewulf   +3 more
wiley   +1 more source

Gender, Social Reproduction and the Construction of Capabilities for Social Sustainability of Agriculture: A Relational Approach

Sustainable Development, EarlyView.
ABSTRACT Farmers' capabilities, a core component of social sustainability, have been largely neglected in sustainable agriculture discourse. Using a relational approach to capabilities and autonomy, this study explores how women farmers translate the opportunity of agricultural innovation into their valued outcomes, and which factors shape their ...
Dawn D. Cheong, Bettina Bock
wiley   +1 more source

Bisphenols and Phthalates in Bottled Mineral Water: First Evidence of Co‐Occurrence, Estrogenic Activity, and Health Risk in Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), its structural analogs, and phthalates are synthetic chemicals widely used, with documented endocrine‐disrupting activity. This study aimed to develop and validate a selective multiresidue analytical method for the simultaneous determination of BPA, 10 bisphenol analogs, and six phthalates in PET‐bottled mineral water.
Giulia Boito Reyes, Lucas Correia Gonçalves, Fernanda Cristina Iba Molinari, José Eduardo Gonçalves   +3 more
wiley   +1 more source

Juvenile and Pubertal Exposure to Polystyrene Nanoplastics Impairs Epididymal Structure and Sperm Quality in Mice

Environmental Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are emerging environmental contaminants capable of crossing biological barriers, accumulating in tissues, and disrupting physiological pathways. The male reproductive system is particularly vulnerable during the postnatal period, a developmental window characterized by intense testicular differentiation and epididymal ...
Gabriel Magalhães Oliveira Rigo, Nicoly Caixêta Gonçalves, Cristiana Livramento Oliveira Pinto, Patrícia Corona Lopes, Raul Silva Santarem, Juliana Reis Machado, Régia Caroline Peixoto Lira, Ana Paula Ramos, Marcos Vinicius da Silva, Hugo Felix Perini, Gláucia Eloisa Munhoz de Lion Siervo   +10 more
wiley   +1 more source

Fetuses exposed to an episode of threatened preterm labor delivered at or near term show signs of cardiac remodeling

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To evaluate whether fetuses exposed to threatened preterm labor (PTL) without intra‐amniotic infection or inflammation (IAI), who were born ≥ 34 weeks' gestation, show signs of cardiac remodeling and dysfunction at admission and 4 weeks after the episode of threatened PTL.
C. Murillo, M. Palacio, C. Rueda, M. Larroya, D. Boada, J. Ponce, M. Guilleumes, O. Gómez, S. Ferrero, E. Gratacós, F. Crispi, T. Cobo   +11 more
wiley   +1 more source