Results 21 to 30 of about 3,336 (181)

Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology

Anais da Academia Brasileira de Ciências, 2001
The ability to introduce genetic modifications in the germ line of complex organisms has been a long-standing goal of those who study developmental biology.
CHARLES BABINET, MICHEL COHEN-TANNOUDJI
doaj   +1 more source

Assessing differences among elasmobranch nurseries to aid conservation based on a genomics framework

Conservation Biology, Volume 40, Issue 4, August 2026.
Abstract Elasmobranch nurseries often differ in environmental conditions, demographics, and use patterns. These differences affect the distribution of genetic variation among nurseries. However, conservation and management strategies often fail to account for such differences because they are difficult to characterize.
Dominic G. Swift, Amanda M. Barker, William B. Driggers III, Bryan S. Frazier, Douglas H. Adams, James J. Gelsleichter, Dana M. Bethea, Bethany M. Deacy, David S. Portnoy   +8 more
wiley   +1 more source

Genetic prescreening of a candidate for laser refractive surgery identifies risk for inadequate tissue response: a case report 

Journal of Medical Case Reports, 2022
Background Inadequate response to corneal laser refractive surgery, e.g., ectatic corneal diseases, may not be identified by conventional examinations, hence creating therapeutic uncertainty.
Andrea Cusumano, Hila Roshanravan, Connie Chao-Shern, Jacopo Sebastiani, Jung Hee Levialdi Ghiron, Larry DeDionisio, Tara Moore   +6 more
doaj   +1 more source

DIAGNÓSTICO MOLECULAR DE ENFERMEDADES GENÉTICAS: DEL DIAGNÓSTICO GENÉTICO AL DIAGNÓSTICO GENÓMICO CON LA SECUENCIACIÓN MASIVA

Revista Médica Clínica Las Condes, 2015
En la actualidad se conocen 8.000 enfermedades genéticas monogénicas. La mayoría de ellas son heterogéneas, por lo que el diagnóstico molecular por técnicas convencionales de secuenciación suele ser largo y costoso debido al gran número de genes ...
Sonia Santillán-Garzón Md., PhD, Dan Diego-Álvarez, PhD, Celia Buades, PhD, Alejandro Romera-López, PhD, Lucía Pérez-Cabornero, PhD, Diana Valero-Hervás, PhD, Diego Cantalapiedra, HGBSC, Bioinformatics, MSc, Vanesa Felipe-Ponce, Gracia Hernández-Poveda, María José Roca, Clara Casañs, Victoria Fernández-Pedrosa, PhD, Carmen Collado M., Ángela Arilla C., Juan Carlos Triviño P., Óscar RodrÍguez C., Guillermo Marco, Mayte Gil, PhD, Rebeca Miñambres, PhD, Alida Ballester, PhD   +20 more
doaj   +1 more source

Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification

International Journal of Cancer, Volume 158, Issue 11, Page 2866-2879, 1 June 2026.
What's new? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez, Carla Debernardi, Alessandra Allione, Elton Jalis Herman, Simonetta Guarrera, Daniela Ferrante, Anna Aspesi, Marika Sculco, Marta La Vecchia, Carlotta Sacerdote, Federica Grosso, Christina M. Lill, Giovanna Masala, Marcela Guevara, Matthias B. Schulze, Salvatore Panico, Yaszan Asgari, Seehyun Park, Giovanna Tagliabue, Anne Tjønneland, Antonio Agudo, Elisabete Weiderpass, Corrado Magnani, Irma Dianzani, Paolo Vineis, Elisabetta Casalone, Giuseppe Matullo   +26 more
wiley   +1 more source

Manipulación genética de seres humanos

ARS Medica, 2006
El gran avance que ha tenido la Genética en los últimos años y, particularmente, aquello relacionado con el desciframiento del genoma humano, ha traído a la discusión pública la posibilidad concreta de manipular genéticamente a los seres humanos.
Manuel Santos Alcántara
doaj   +1 more source

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

Veterinary Dermatology, Volume 37, Issue 3, Page 365-374, June 2026.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake, Melissa P. Swan, Kari J. Ekenstedt   +2 more
wiley   +1 more source

Development of a plant growth-promoting bacterial EcoBiome derived from desert soil isolates

Applied and Environmental Microbiology
The study of the application of plant growth-promoting (PGP) bacteria has increased due to their potential to enhance crop yield, improve nutrient acquisition, and increase plant tolerance to biotic and abiotic stresses.
Camila Albarrán-Cuitiño, Daniel E. Palma, Hugo González, José Antonio O'Brien, Mauricio González, Alexis Gaete   +5 more
doaj   +1 more source

Genomas, más genomas

, 2014
Lección inaugural del Curso Académico 2014/2015 en las Universidades Públicas de la Región de Murcia, a cargo del catedrático Francisco José Murillo Araujo.
openaire   +2 more sources

Ancient hybridization and phylogenetic discordance: Exploring evolutionary complexity in Asteraceae

Applications in Plant Sciences, Volume 14, Issue 3, May-June 2026.
Abstract Premise Conflicting phylogenetic signals are common in plant phylogenomics and often reflect evolutionary histories shaped by processes like hybridization, incomplete lineage sorting, and whole‐genome duplication (WGD). We aimed to identify and assess these complex processes in the hyper‐diverse family Asteraceae to offer insight into the ...
Paige A. Ellestad, Erika R. Moore‐Pollard, Carolina M. Siniscalchi, Ramhari Thapa, Linda E. Watson, J. Mauricio Bonifacino, Jennifer R. Mandel   +6 more
wiley   +1 more source