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The Evolution of Bacterial Genome Architecture [PDF]
The genome architecture of bacteria and eukaryotes evolves in opposite directions when subject to genetic drift, a difference that can be ascribed to the fact that bacteria exhibit a mutational bias that deletes superfluous sequences, whereas eukaryotes ...
Louis-Marie Bobay, Howard Ochman
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Bacterial Genomics and Epidemiology
Innovative technologies for Whole-Genome Sequencing (WGS) help to improve our understanding of the epidemiology and pathogenesis of bacterial infectious diseases and are becoming affordable for most microbiological laboratories [...]
Javier Garaizar, Lorena Laorden
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During the last decade, great advances have been made in the study of bacterial genomes which is perhaps better described by the term bacterial genomics. The application of powerful techniques, such as pulsed-field gel electrophoresis of macro-restriction fragments of genomic DNA, has freed the characterisation of the chromosomes of many bacteria from ...
S T, Cole, I, Saint Girons
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The layout of a bacterial genome [PDF]
Recently the mismatch between our newly acquired capacity to synthetize DNA at genome scale, and our low capacity to design ab initio a functional genome has become conspicuous. This essay gathers a variety of constraints that globally shape natural genomes, with a focus on eubacteria.
François Képès+6 more
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Conspiracy in bacterial genomes [PDF]
The rank ordered distribution of the codon usage frequencies for 123 bacteriae is best fitted by a three parameters function that is the sum of a constant, an exponential and a linear term in the rank n. The parameters depend (two parabolically) from the total GC content.
Frappat, Luc, Sciarrino, Antonino
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Insights in bacterial genome folding [PDF]
Chromosomes in all domains of life are well-defined structural entities with complex hierarchical organization. The regulation of this hierarchical organization and its functional interplay with gene expression or other chromosome metabolic processes such as repair, replication, or segregation is actively investigated in a variety of species, including
Yáñez-Cuna, Fares Osam, Koszul, Romain
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Bacterial Genome Instability [PDF]
SUMMARY Bacterial genomes are remarkably stable from one generation to the next but are plastic on an evolutionary time scale, substantially shaped by horizontal gene transfer, genome rearrangement, and the activities of mobile DNA elements. This implies the existence of a delicate balance between the maintenance of genome stability and the ...
Elise Darmon, David R. F. Leach
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Background Plasmodium falciparum (Pf) whole-organism sporozoite vaccines have been shown to provide significant protection against controlled human malaria infection (CHMI) in clinical trials.
Kara A. Moser+33 more
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fIDBAC: A Platform for Fast Bacterial Genome Identification and Typing
To study the contamination of microorganisms in the food industry, pharmaceutical industry, clinical diagnosis, or bacterial taxonomy, accurate identification of species is a key starting point of further investigation.
Qian Liang+13 more
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Genome-guided insight into the methylotrophy of Paracoccus aminophilus JCM 7686
Paracoccus aminophilus JCM 7686 (Alphaproteobacteria) is a facultative, heterotrophic methylotroph capable of utilizing a wide range of C1 compounds as sole carbon and energy sources.
Lukasz eDziewit+6 more
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