Results 41 to 50 of about 230,429 (298)

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +2 more sources

Local Population Structure and Patterns of Western Hemisphere Dispersal for Coccidioides spp., the Fungal Cause of Valley Fever. [PDF]

, 2016
UnlabelledCoccidioidomycosis (or valley fever) is a fungal disease with high morbidity and mortality that affects tens of thousands of people each year. This infection is caused by two sibling species, Coccidioides immitis and C.
Arathoon, Eduardo, Barker, Bridget, Chiller, Tom, Driebe, Elizabeth M, Engelthaler, David M, Gade, Lalitha, Hepp, Crystal M, Keim, Paul, Komatsu, Kenneth, Litvintseva, Anastasia P, Logemann, Heidi, Roe, Chandler C, Schupp, James M, Teixeira, Marcus, Thompson, George R, Waddell, Victor   +15 more
core   +3 more sources

Fungal genome resources at NCBI

Mycology, 2011
The National Center for Biotechnology Information (NCBI) is well known for the nucleotide sequence archive, GenBank and sequence analysis tool BLAST. However, NCBI integrates many types of biomolecular data from variety of sources and makes it available to the scientific community as interactive web resources as well as organized releases of bulk data.
B, Robbertse, T, Tatusova
openaire   +2 more sources

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

Angewandte Chemie, EarlyView.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson, Madouc D. Bergers, David N. Bolam, Ana S. Luis, Alan Cartmell, Zachary Armstrong   +5 more
wiley   +2 more sources

Widespread bacterial diversity within the bacteriome of fungi

Communications Biology, 2021
Robinson et al. explore bacterial associations in over 700 phylogenetically diverse fungal isolates with 16 S rRNA sequencing of fungal collections from across the globe and bioinformatic screening of publicly available fungal genome sequencing projects.
Aaron J. Robinson, Geoffrey L. House, Demosthenes P. Morales, Julia M. Kelliher, La Verne Gallegos-Graves, Erick S. LeBrun, Karen W. Davenport, Fabio Palmieri, Andrea Lohberger, Danaé Bregnard, Aislinn Estoppey, Matteo Buffi, Christophe Paul, Thomas Junier, Vincent Hervé, Guillaume Cailleau, Simone Lupini, Hang N. Nguyen, Amy O. Zheng, Luciana Jandelli Gimenes, Saskia Bindschedller, Debora F. Rodrigues, James H. Werner, Jamey D. Young, Pilar Junier, Patrick S. G. Chain   +25 more
doaj   +1 more source

Shallow Genome Sequencing for Phylogenomics of Mycorrhizal Fungi from Endangered Orchids [PDF]

, 2019
Most plant species form symbioses with mycorrhizal fungi and this relationship is especially important for orchids. Fungi in the genera Tulasnella, Ceratobasidium, and Serendipita are critically important for orchid germination, growth and development ...
Barry, Kerrie, Daum, Christopher, Erba, Luigi, Grigoriev, Igor, Lipzen, Anna, Pires, Chris, Stajich, Jason, Unruh, Sarah, Zettler, Lawrence   +8 more
core  

Spontaneous circadian rhythms in a cold-Adapted natural isolate of Aureobasidium pullulans [PDF]

, 2017
Indexación: Scopus.Circadian systems enable organisms to synchronize their physiology to daily and seasonal environmental changes relying on endogenous pacemakers that oscillate with a period close to 24 h even in the absence of external timing cues. The
Bellora, N., Canessa, P., Franco, D.L., Larrondo, L.F., Libkind, D., Marpegan, L., Olivares-Yañez, C., Pérez-Lara, R., Risau-Gusman, S.   +8 more
core   +3 more sources

Neurospora from natural populations: Population genomics insights into the Life history of a model microbial Eukaryote [PDF]

, 2020
The ascomycete filamentous fungus Neurospora crassa played a historic role in experimental biology and became a model system for genetic research. Stimulated by a systematic effort to collect wild strains initiated by Stanford geneticist David Perkins ...
A Menkis, A Pandit, A Pandit, A Pringle, A Stamatakis, AJ Powell, BC Turner, BO Dodge, BO Dodge, BO Dodge, C Roux, CA Muirhead, CE Ellison, CF Villalta, CL Shear, D Bryant, D Charlesworth, D Falush, DD Perkins, DD Perkins, DD Perkins, DD Perkins, DD Perkins, DD Perkins, DJ Jacobson, DJ Jacobson, DJ Jacobson, DK Aanen, E Frichot, E Turner, E Turner, EM Luque, GS Saenz, GW Beadle, H Akashi, H-C Kuo, HV Colot, J Dettman, J Heller, J Heller, J Palma-Guerrero, J Svedberg, J Zhao, JB Leducq, JE Galagan, JE Stajich, JF Wilson, JK Pritchard, JR Dettman, JR Dettman, JW Taylor, JW Taylor, JW Taylor, K Kitazima, K Nygren, KR Pomraning, MJ Hubisz, MP Skupski, NB Raju, NG Swenson, NH Horowitz, NL Glass, NL Glass, P Ad, P Corcoran, P Corcoran, P Corcoran, P Corcoran, P Gladieux, P Gladieux, P Gladieux, PR Neal, RH Davis, RH Davis, RN Gutenkunst, S Billiard, S Mita De, S Poggeler, T Giraud, TE Cruickshank, YF Li   +80 more
core   +2 more sources