Results 11 to 20 of about 313,429 (269)
Modifying the Mitochondrial Genome [PDF]
Cell Metabolism, 2016 Human mitochondria produce ATP and metabolites to support development and maintain cellular homeostasis. Mitochondria harbor multiple copies of a maternally inherited, non-nuclear genome (mtDNA) that encodes for 13 subunit proteins of the respiratory chain.
Patananan, Alexander N +3 more
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Lophotrochozoan mitochondrial genomes [PDF]
Integrative and Comparative Biology, 2006 Progress in both molecular techniques and phylogenetic methods has challenged many of the interpretations of traditional taxonomy. One example is in the recognition of the animal superphylum Lophotrochozoa (annelids, mollusks, echiurans, platyhelminthes, brachiopods, and other phyla), although the relationships within this group and the inclusion of ...
Valles, Yvonne, Boore, Jeffrey L.
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The ageing mitochondrial genome [PDF]
Nucleic Acids Research, 2007 The population of elderly individuals has increased significantly over the past century and is predicted to rise even more rapidly in the future. Ageing is a major risk factor for many diseases such as neurodegenerative disease, diabetes and cancer. This highlights the importance of understanding the mechanisms involved in the ageing process.
Krishnan, Kim J. +3 more
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Mitochondrial helicases and mitochondrial genome maintenance [PDF]
Mechanisms of Ageing and Development, 2010 Helicases are essential enzymes that utilize the energy of nucleotide hydrolysis to drive unwinding of nucleic acid duplexes. Helicases play roles in all aspects of DNA metabolism including DNA repair, DNA replication and transcription. The subcellular locations and functions of several helicases have been studied in detail; however, the roles of ...
de Souza-Pinto, Nadja C +4 more
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Mitochondrial DNA. Part B. Resources, 2020 In this study, the complete mitochondrial genome of Sterigmatomyces hyphaenes was sequenced by the next-generation sequencing. The complete mitochondrial genome of S. hyphaenes contained 17 protein-coding genes (PCG), 2 ribosomal RNA (rRNA) genes, and 23
Maoling Tan, Qiangfeng Wang
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Editing the Mitochondrial Genome
New England Journal of Medicine, 2020 Mending Mitochondrial Mutation For most patients with mitochondrial disorders, most of which are caused by mutations in genes in the mitochondrial genome, only symptomatic treatment is available.
Maria Falkenberg, Michio Hirano
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The complete mitochondrial genome of Xenopsylla cheopis (Siphonaptera: Pulicidae)
Mitochondrial DNA. Part B. Resources, 2022 Xenopsylla cheopis, also called oriental rat flea, is an ectoparasite as well as disease vector for murine typhus and bubonic plague. In the study, the whole mitochondrial genome of X.
Furong Wei +6 more
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The Oxytricha trifallax Mitochondrial Genome [PDF]
Genome Biology and Evolution, 2011 The Oxytricha trifallax mitochondrial genome contains the largest sequenced ciliate mitochondrial chromosome (~70 kb) plus a ~5-kb linear plasmid bearing mitochondrial telomeres. We identify two new ciliate split genes (rps3 and nad2) as well as four new mitochondrial genes (ribosomal small subunit protein genes: rps- 2, 7, 8, 10), previously ...
Swart, Estienne C +10 more
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Nature Communications, 2016 The post-transcriptional 5-methylcytosine (m5C) modification occurs in a wide range of nuclear-encoded RNAs. Here the authors identify the mitochondrial tRNA-Met as a target for the m5C methyltransferase NSun3—found mutated in a mitochondrial disease ...
Lindsey Van Haute +18 more
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Mitochondrial DNA. Part B. Resources, 2022 Crematogaster matsumurai (Forel 1901) is an important arboreal ant species commonly found on Phyllostachys heterocycla (Carr.) in Lishui, Zhejiang, China. This study analyzed the mitochondrial genome sequence of C.
Jin-chao Wang +6 more
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