Results 221 to 230 of about 313,429 (269)

The mitochondrial genome of yeast

Cell, 1978
mtDNA is the simplest DNA in nature which carries genes for the three classes of RNA-rRNAs, tRNAs, and mRNAs. In yeast, this genetic system has a number of unusual features that may even be of interest to molecular biologists who do not particularly care about mitochondrial biogenesis: -The gene for the large rRNA is split and the intervening sequence ...
P, Borst, L A, Grivell
openaire   +2 more sources

Deletions of the mitochondrial genome

Journal of Inherited Metabolic Disease, 1992
SummarySingle large deletions of mitochondrial DNA are found in the muscle of about 40% of patients with mitochondrial myopathies, and are detectable in both blood and muscle in Pearson syndrome. In mitochondrial myopathies, there is a close association between the presence of deletions and involvement of extra‐ocular muscles, together with other ...
A E, Harding, S R, Hammans
openaire   +2 more sources

Mitochondrial fusion and inheritance of the mitochondrial genome

Journal of Plant Research, 2010
Although maternal or uniparental inheritance of mitochondrial genomes is a general rule, biparental inheritance is sometimes observed in protists and fungi,including yeasts. In yeast, recombination occurs between the mitochondrial genomes inherited from both parents.Mitochondrial fusion observed in yeast zygotes is thought to set up a space for DNA ...
Hiroyoshi, Takano, Kenta, Onoue, Shigeyuki, Kawano   +2 more
openaire   +2 more sources

The mitochondrial genome and mitochondrial muscle disorders

Current Opinion in Pharmacology, 2001
Mitochondrial disorders represent a multitude of clinically heterogeneous diseases in which the genetic abnormality can involve either a mitochondrial or nuclear gene. In addition to inherited defects, somatic mitochondrial DNA mutations have been implicated in the pathogenesis of neurodegenerative disease, cancer and the ageing process.
A M, Schaefer, R W, Taylor, D M, Turnbull   +2 more
openaire   +2 more sources

The mitochondrial genome. The nucleoid

Biochemistry (Moscow), 2016
Mitochondrial DNA (mtDNA) in cells is organized in nucleoids containing DNA and various proteins. This review discusses questions of organization and structural dynamics of nucleoids as well as their protein components. The structures of mt-nucleoid from different organisms are compared.
openaire   +2 more sources

The influence of mitochondrial dynamics on mitochondrial genome stability

Current Genetics, 2017
Mitochondria are dynamic organelles that fuse and divide. These changes alter the number and distribution of mitochondrial structures throughout the cell in response to developmental and metabolic cues. We have demonstrated that mitochondrial fission is essential to the maintenance of mitochondrial DNA (mtDNA) under changing metabolic conditions in ...
Christopher T, Prevost, Nicole, Peris, Christina, Seger, Deanna R, Pedeville, Kathryn, Wershing, Elaine A, Sia, Rey A L, Sia   +6 more
openaire   +2 more sources

Mitochondrial genetics of Coprinus: Recombination of mitochondrial genomes

Current Genetics, 1983
The formation of the sexual mycelium or dikaryon in the basidiomycete Coprinus cinereus involves exchange and migration of nuclei without accompanying exchange of mitochondria. The dikaryotic growth which appears around the periphery of mated monokaryons has exclusively the mitochondrial genome of the recipient cells.
J L, Baptista-Ferreira, A, Economou, L A, Casselton   +2 more
openaire   +2 more sources

Mitochondrial Genomes of the Ciliates

1992
Publisher Summary This chapter describes the mithochondrial genome of ciliates, with emphasis on Paramecium and Tetrahymena . Both Paramecium and Tetrahymena have linear genomes with unique replicative pathways. The mitochondrial genome of Paramecium aurelia is a linear duplex.
openaire   +2 more sources

Evidence that the mitochondrial genome is the thrifty genome

Diabetes Research and Clinical Practice, 1999
Although mitochondrial DNA (mtDNA) abnormalities are known to cause insulin deficiency, insulin resistance and diabetes mellitus, it's quantitative aspect was not addressed well. In this review, mitochondrial genome hypothesis of thrifty phenomenon is proposed, based on the data and review of literatures. From a population based epidemiologic study, it
openaire   +2 more sources

TRANSCRIPTION OF THE MAMMALIAN MITOCHONDRIAL GENOME

Annual Review of Biochemistry, 1984
PERSPECTIVES AND SUMMARY 573 GENOMIC ORGANIZATION 574 TRANSCRIPTIONAL MAPPING 576 INITIATION, ELONGATION, AND TERMINATION OF TRANSCRIPTION 578 I n Vivo Transcription 578 In Vitro Transcription 581 PROCESSING OF PRIMARY TRANSCRIPTS 582 POST-TRANSCRIPTIONAL MODIFICATION AND MATURATION OF RNA ..•..• ••...• 584 Ribosomal RN As 584 Transfer ...
openaire   +2 more sources